introduction dna damage is among the main consequences of radiation. of many different classes of dna damage, double-strand breaks are the most deleterious. development of a sensitive biodosimetry method, which utilizes a detection material with a similar construction to the body, seems essential for monitoring radiation workers. in this study, histone h2ax protein was examined as a potential  ...

PURPOSE Advances in medical imaging have been associated with increased utilization and increased radiation exposure, especially for patients with chronic and recurrent conditions. The authors estimated the cumulative radiation doses from medical imaging for specific cohorts with chronic and recurrent conditions. METHODS All patients diagnosed with hydrocephalus (n = 1,711), pulmonary thrombo...

BACKGROUND The growing use of imaging procedures in the United States has raised concerns about exposure to low-dose ionizing radiation in the general population. METHODS We identified 952,420 nonelderly adults (between 18 and 64 years of age) in five health care markets across the United States between January 1, 2005, and December 31, 2007. Utilization data were used to estimate cumulative ...

Background: Environmental ionizing radiation has been associated with increased cancer risk by several studies.  The Brazilian city of Poços de Caldas, MG, seats on a huge deposit of uranium, which was until recently mined.  We performed a retrospective analysis of  310 cases of patients with breast cancer, who were exposed for at least ten years to different levels of ion...

Evidence of health benefits and longer average life-span following low-dose irradiation should replace fear, “all radiation is harmful,” and “the perception of harm” as the basis for action in the 21 century. Hormesis is the excitation, or stimulation, by small doses of any agent in any system. Large doses inhibit. “Low dose” is defined as any dose between ambient levels of radiation and the th...

Introduction: Computed tomography (CT) is a medical imaging modality that produces 3-D cross-sectional images of tissues using several X-ray projections at different angles. Since its introduction in the 1970s, CT usage has been on the increase for both adults and pediatrics. A major challenge of this modality is the high doses of radiation exposure to patients, especially in p...

developed tumors depended on the number of viable cells inoculated. For this paper the same• technic was used to study the effect of x-radiation on tumor cells in suspension : first, to establish the lethal effect of equal doses of radiation on different concentrations of tumor cells; second, to deter mine the influence of radiation on the growth pe riod; third, to determine whether any radia...

PURPOSE Cancer stem cells (CSCs) may play a role in the recurrence of glioblastoma. They are believed to originate from neural stem cells in the subventricular zone (SVZ). Because of their radioresistance, we hypothesized that high doses of radiation (>59.4 Gy) to the SVZ are necessary to control CSCs and improve progression-free survival (PFS) or overall survival (OS) in glioblastoma. METHOD...

One of the most important developments in radiobiology in recent years has been a change in the concept of the ability of the nervous system to withstand the effects of ionizing radiation. Until recently it had been generally believed that the tissue of the nervous system was especially resistant to radiation and that any kind of damage to it could occur only at extremely high radiation doses. ...