Hapten sensitization through UV-exposed skin induces hapten-specific tolerance which can be adoptively transferred by injecting T cells into naive recipients. The exact phenotype of the regulatory T cells responsible for inhibiting the immune response and their mode of action remain largely unclear. Dectin-2 is a C-type lectin receptor expressed on APCs. It was postulated that dectin-2 interact...

Recently, autonomous vehicles and robots demand high-speed image recognition capability that is superior to that of the human eye, in addition to capability of recognizing various natural images just like humans can. However, to realize both, the bus bandwidth of current memories is insufficient. Such an embedded system necessitates the use of numerous highresolution template images on a memory...

The development of fault-tolerant autonomous robots for long-term deployment has been an area of active research for decades. Many researchers have focused on the tolerance to failures of sensors and actuators of various types of robots. In contrast to these failures, robots encounter transient faults on all levels including the bit level of microprocessors when operating in space or in nuclear...

Background Chemoradiation has shown superior overall survival when compared with radiation alone in esophageal carcinoma. Due to compromised nutritional status, radiation therapy in esophageal cancer patients itself is a challenge and addition of concurrent chemotherapy leads to severe side effects even when standard dose regimens are used. The tolerance of chemoradiation for carcinoma esophagu...

For the potential use in future high luminosity applications in High Energy Physics (HEP) (e.g. the Large Hadron Collider (LHC) upgrade), we evaluated the radiation tolerance of several candidate technologies for the front-end of the readout ApplicationSpecific Integrated Circuit (ASIC) for silicon strip detectors. The devices investigated were first, second and third-generation SiliconGermaniu...

Modified atmosphere packaging (MAP) produces a low-oxygen (O2) environment that can increase produce shelf life by decreasing product respiration and growth of pathogens. However, low O2 is known to increase insect tolerance to irradiation, and the use of MAP with products treated by irradiation before export to control quarantine pests may inadvertently compromise treatment efficacy. Melon fly...

A grand challenge in material science is to understand the correlation between intrinsic properties and defect dynamics. Radiation tolerant materials are in great demand for safe operation and advancement of nuclear and aerospace systems. Unlike traditional approaches that rely on microstructural and nanoscale features to mitigate radiation damage, this study demonstrates enhancement of radiati...

Radiation therapy can be an effective way to kill cancer cells using ionizing radiation, but some tumors are resistant to radiation therapy and the underlying mechanism still remains elusive. It is therefore necessary to establish an appropriate working model to study and monitor radiation-mediated cancer therapy. In response to cellular stress, the metabolome is the integrated profiling of cha...

Research on penetration of ultraviolet (UV) radiation into human skin shows that about 20% of UVA and 10% of UVB can reach the basal layer of the epidermis. As a consequence, Langerhans cells (LCs), located in suprabasal layers, are subject to the influence of the two types of UV radiation. This phenomenon leads to quantitative and qualitative alterations in LCs, including reduction in their nu...

Climate change with the impact of drought stress has become a major environmental problem for rice ( Oryza sativa L.). The use gamma ray radiation at dose 300 Gy is one way to develop tolerant varieties little characteristics Towuti variety. However, research still needed determine its resistance stress. This study aims identify characters selection, genotype and response mutant conditions. tha...