Sporadic non-toxic goitre (SNG) is defined as thyroid enlargement in a euthyroid patient living in an area without endemic goitre. Because thyroid hormone function is within the reference range, the main problems are the signs of thyroid enlargement, thus reducing the size of the goitre is undoubtedly the primary goal of therapy. Although SNG is a common disease, there is no single optimal mana...

Since first discovered just 35 years ago, the incidence of spontaneous feline hyperthyroidism has increased dramatically to the extent that it is now one of the most common disorders seen in middle-aged to senior domestic cats. Hyperthyroid cat goiters contain single or multiple autonomously (i.e. TSH-independent) functioning and growing thyroid nodules. Thus, hyperthyroidism in cats is clinica...

introduction:  the use of radioactive iodine (131i) has become an important adjunct to the treatment of thyroid cancer and hyperthyroidism. salivary gland has the ability to concentrate radioactive iodine under normal circumstances. salivary gland dysfunction and dry mouth are the common side effectsof high-dose radioiodine therapy. the purposeof this study was to determine the absorbed dose of...

BACKGROUND subclinical hyperthyroidism (SHT) is associated with harmful effects on cardiovascular system, bone metabolism and progression to clinical hyperthyroidism. Loss of weight is a common fact in patients with clinical hyperthyroidism and of particular relevance in elderly patients. OBJECTIVE to assess changes in body composition after radioiodine therapy for SHT due to toxic nodular go...

UNLABELLED Therapeutic options for toxic thyroid nodules (TTNs) are surgery, radioiodine (RAI), and percutaneous ethanol injection (PEI). Surgery is generally considered for TTNs larger than 4 cm. However, some patients may be at high surgical risk. The purpose of the study was to evaluate the efficacy of 2 nonsurgical modalities for these TTNs. METHODS Twenty-two patients with TTNs larger th...

objective(s): the aim of this study was to determine whether high-dose radioactive iodine (na131i) outpatient treatment of patients with thyroid carcinoma is a pragmatically safe approach, particularly for the safety of caregivers. methods: a total of 79 patients completed the radiation-safety questionnaires prior to receiving high-dose radioactive iodine treatment. the questionnaire studied th...

OBJECTIVE To evaluate 131I therapy in elderly patients with subclinical hyperthyroidism (SCH) due to nodular disease and who did not receive antithyroid drugs (ATDs), and the effect of the treatment on bone metabolism. SUBJECTS AND METHODS Thirty-six patients with TSH ≤ 0.1 mIU/L and non-voluminous goiter (< 60 cm³) were studied. Bone mineral density (BMD) was assessed in 17 women with osteop...

yperthyroidism is a common endocrine disorder. A recent national survey found a prevalence of 0.5% in the general US population. The most common cause of hyperthyroidism is Graves’ disease, which accounts for 80% to 90% of cases. Three treatment options currently are available for patients with Graves’ disease: radioiodine therapy, antithyroid drugs, and thyroidectomy. The clinician should choo...

INTRODUCTION Suspicion of a neoplasm is one of the contraindications to radioiodine therapy in benign thyroid disease. The aim of this study was to present an optimal qualification scheme for fine-needle aspiration biopsy (FNAB) to rule out neoplastic lesions prior to radioiodine therapy. MATERIAL AND METHODS 4207 patients with hyperthyroidism were referred for 131I therapy in 2000-2006. Prio...

BACKGROUND Few data are available on therapy-related myelodysplastic syndromes and acute myeloid leukemia developing after radioiodine treatment. DESIGN AND METHODS We retrospectively analyzed 39 patients with myeloid neoplasms following radioiodine treatment, whose data were reported to the Duesseldorf Myelodysplastic Syndromes Register (8 of 3814 patients) and five other German Myelodysplas...