multiple sclerosis is a chronic inflammatory disease of central nervous system.women are more susceptible to this disease. one of the obvious clinical complaints in women with multiple sclerosis specially treated with beta interferones is menstrual cycle irregularity. the aim of this study was to determine the prevalence of menstrual irregularities and probable changes in blood levels of relate...

multiple sclerosis (ms) is a neuroinflammatory autoimmune disease which mediated by various molecular and cellular immune components however recent reports have shown that coagulation factors that traditionally separate from the immune system might also be involved in ms development and progression.studies on experimental autoimmune encephalomyelitis (eae) and human ms patients reports alterati...

multiple sclerosis (ms) is one of the autoimmune diseases with an unknown cause. the aim of this study was to explore the link between air quality and ms relapses in patients who suffer from ms.this time-series study was conducted on patients registered at the iranian multiple sclerosis society in 2011-2012. they were randomly selected from patients lived in tehran in the last five years, and h...

autoimmune diseases have been described as an interesting and poorly understood group of disorders. there are many challenges in the respective scientific societies concerning the nature, causes and the therapeutic approaches of these diseases. in accordance with the evidences the nature and etiology of these disorders is multifactorial and complex but the clearest definition could be expressed...

multiple sclerosis is an autoimmune disease caused by damage to the myelin of the nerve cells in the spinal cord and brain, ms was classified into 4 types including: relasping/remitting (rr) primary/progressive (pp), secondary/progressive (sp), progressive/relapsing (pr). pr ms is one of the severe forms of ms that lead to inflammation associated physical, mental and vision dysfunction. because...

noncoding ribonucleic acids micro-rna is involved in the regulation of gene expression have major roles in the post-transcriptional level. a micro-rna alone several causes down regulation of mrna transcript of the target. thus, small changes in the expression of a micro rna may lead to significant changes in gene expression are different. micro- rna as key regulators of immune cell lineage diff...

multiple sclerosis is an autoimmune disease of the central nervous system which its main characteristic is an inflammation and demyelination and subsequent, neural degeneration. many studies have shown that inflammation causing neuronal demyelination. ms is the most common cause of chronic neurological disability in during youth which the prognosis is that can be death. platelet activating fact...

guillain-barre syndrome (gbs) or acute idiopathic polyradiculoneuritis is an acquired immune-mediated inflammatory and mainly demyelinating disorder of the peripheral nervous system. cranial nerves are affected in over 50% of all cases, with the facial nerves being affected the most. it uncommonly presents as atypical forms such as brachial pharyngeal variant, miller fisher and other restricted...

background: initial symptoms of multiple sclerosis (ms) may be varied and nonspecific. we tried to find the frequency distribution of the first clinical symptoms in iranian patients with ms. methods: in a case series study, 1130 patients with definite diagnosis of ms who had been referred to three referral university hospitals of tehran, iran, were enrolled. the patients' medical records were r...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: the efficacy of mitoxantrone induction therapy in rapidly worsening multiple sclerosis (ms) is well established. plasma exchange is also applied as an adjuvant in exacerbations of relapsing ms. the aim of this study was to compare the efficacy of combination therapy with mitoxantrone and plasma exchange versus ...