Objective(s): Curcumin, a natural plant product, is commonly known as wonder drug of life, but the poor bioavailability of its free form has hindered its clinical development. The aim of the present study was to investigate the radioprotective effect of nanocurcumin on survival of mice under whole body X-ray irradiation. Materials and Methods: The Naval Medical Research Institute (NMRI) mice ra...

Ionizing radiations produce deleterious effects in the living organisms and the rapid technological advancement has increased human exposure to ionizing radiations enormously. There is a need to protect humans against such effects of ionizing radiation. Attempts to protect against the deleterious effects of ionizing radiations by pharmacological intervention were made as early as 1949 and effor...

The radioprotective effects of water-soluble derivate of propolis (WSDP) collected in Croatia, and single flavonoids, caffeic acid, chrysin and naringin in the whole-body irradiated CBA mice were investigated. Irradiation was performed using a gamma-ray source ((60)Co), and absorbed doses were 4 and 9 Gy. The efficiency of test components was evaluated when given intraperitoneally (i.p.) at dos...

The development of radioprotective agents has been a subject of intense research in view of their potential for use within a radiation environment, such as space exploration, radiotherapy and even nuclear war. Since no ideal, safe synthetic radioprotectors are available to date, the search for alternative sources, including plants, has been on-going for several decades. In the Traditional India...