Vascular changes in a transplantable neuroblastoma of A/J mice following X-irradiation were studied. X-irradiation with doses lower than 500 rads in a single exposure caused a slight increase in the functional intravascular volume, as measured with s ' Cr-labeled red cells 1 day after the irradiation, and a gradual decrease thereafter. X-irradiation with 1000 and 2000 rads, in contrast, induced...

Methods We evaluated relationships between mammographic density and risk of death from breast cancer and all causes within the US Breast Cancer Surveillance Consortium. We studied 9232 women diagnosed with primary invasive breast carcinoma during 1996–2005, with a mean follow-up of 6.6 years. Mammographic density was assessed using the Breast Imaging Reporting and Data System (BI-RADS) density ...

To evaluate radiometal-labeled humanized BrE-3 (huBrE-3) monoclonal antibody as a radioimmunolocalization and therapeutic agent in breast cancer patients, tumor localization, pharmacokinetics, radiation dosimetry, and immunogenicity of (111)In-labeled combined 1-p-isothiocyanatobenzyl 3-methyl- and 1-p-isothiocyanatobenzyl 4-methyldiethylenetriamine pentaacetic acid (MX-DTPA) huBrE-3 were studi...

PURPOSE The aim of this study was to compare the performance of image analysis for predicting breast cancer using two distinct regression models and to evaluate the usefulness of incorporating clinical and demographic data (CDD) into the image analysis in order to improve the diagnosis of breast cancer. METHODS This study included 139 solid masses from 139 patients who underwent a ultrasonogr...

BACKGROUND The density of breast tissue on a mammogram is a strong predictor of breast cancer risk and may reflect cumulative estrogen effect on breast tissue. Endogenous and exogenous estrogen exposure increases the risk of estrogen receptor (ER)-positive breast cancer. We determined if mammographic density is associated more strongly with ER-positive breast cancer than with ER-negative breast...

BACKGROUND Several studies, which were limited by their small sample size and selection of difficult cases for review, have reported substantial variability among radiologists in interpretation of mammographic examinations. We have determined, in the largest study to date, intraobserver and interobserver agreement in interpreting screening mammography and accuracy of mammography by use of the A...

To investigate the diagnostic value of breast ultrasound breast imaging reporting and data system (BIRADS) classification combined with transforming growth factor-β (TGF-β) detection to differentiate malignant from benign tumors. This study enrolled 163 patients with breast tumor (breast cancer of 104 cases and breast benign tumor of 59 cases) who were admitted to Cangzhou Central Hospital from...