SUMMARY Adult male Sprague-Dawley rats briefly immersed-n cold water and forced to swim showed Straub tail elevation, a typical s~gn of opiate stimu-iation, upon removal. The presence of Straub tail was a function of degree of immersion and was reversed by naloxone. Th~s suggests the Straub taft response may be a novel behavioral index of stress-indu~ed endorphin release. Stressful manipulation...

Intact mammalian neurofilaments were separated by centrifugation of osmotically shocked, desheathed segments of rat peripheral nerve. Neurofilament-rich supernates were incubated in different media with varying dilutions or dialysis of samples. Neurofilaments attached to carbon-Formvar-coated grids were exposed to similar incubations. The relative preservation or disruption of neurofilaments du...

Urinary sodium output increases in the first several days of fasting both in humans and rabbits. The major causal factor of the fasting-induced natriuresis was proposed to be glucagon (1), but the mechanism remains obscure. We have recently observed that fasting for one to four days resulted in the negative sodium balance in rats provided a low salt diet and saline (2). The fasting-induced natr...

Background: Amylin and Salmon Calcitonin belong to the calcitonin family of peptides and have high affinity binding sites in the rat spinal cord. The aim of this study was to characterize receptors for Amylin and Salmon Calcitonin functionally in the spinal cord of rats. We assessed the expression of c-Fos in response to intraplantar formalin in the lumbar regions of the spinal cord in consciou...

Sll?gested the clinical picture of cholera. . There had been no cases of cholera howevei 1,1 the village in which he lived. Without Raiting to make a diagnosis, 1 gave him two pints of hypertonic saline solution with glucose and adrenalin intravenously. I also ordered 10 minims of liquor adrenalin hydrochloride to be dropped under the tongue even l0ur for six doses. When I saw the patient six h...

INTRODUCTION Patients with chronic liver diseases are usually thin as a result of hypermetabolism and malnutrition expressed by reduced levels of leptin and impairment of other adyponectins such as visfatin. AIMS We evaluated the metabolic and inflammatory effects of intravenous high-dose furosemide plus hypertonic saline solutions (HSS) compared with repeated paracentesis and a standard oral...

The involvement of spinal column in cyst hydatid disease is rare and hard to treat. The gold standard treatment is total removal of the cysts without rupture. However, recurrence after surgery is almost inevitable and reoperations carries technical difficulties and higher morbidity. We present a 69-year-old woman with two cystic masses at the T12 level, which compress the spinal...

STUDY OBJECTIVE To elucidate the mechanism of hyperpnea and tachypnea, which are the common findings in cardiopulmonary patients. RATIONALE Recently, it was found that activating pulmonary afferents by directly injecting hypertonic saline solution into the lung periphery causes a vagally mediated neural hyperpnea and tachypnea, ie, the excitatory lung reflex. Since reactive oxygen species are...

Maternal separation (MS) has been demonstrated to up-regulate the hypothalamic vasopressin (VP) system. Intracerebrally released VP has been demonstrated to affect several types of animal behaviour, such as active/passive avoidance, social recognition, and learning and memory. However, the role of VP in spatial learning remains unclear. In the present study, we investigated the effects of an os...

Hypertonic saline solution can absorb part of the intracellular fluid volume into the extracellular space. The effects of this solution on the cardiovascular system are increased coronary flow and increased left ventricular contraction, without sympathetic system activation. This study was designed to assess the effects of hypertonic saline solution in open heart surgery and to compare it w...