نتایج جستجو برای: recombinant core

تعداد نتایج: 324308  

Journal: :avicenna journal of medical biotechnology 0

background: staphylococcus aureus (s. aureus) is a major nosocomial pathogen and the infection with this organism in human is increasing due to the spread of antibiotic resistant strains. one of the resistance mechanisms of s. aureus comprises modification in binding proteins to penicillin. vaccine strategy may be useful in controlling the infections induced by this organism. this study aimed a...

Journal: :iranian journal of immunology 0
fatemeh malaei biology research center, faculty of science, imam hussein university mahdi hesaraki department of stem cell and developmental biology, cell science research center, royan institute for stem cell biology and technology, acecr, tehran mojtaba saadati biology research center, faculty of science, imam hussein university ali mohammad ahdi department of genetics, faculty of science, shahrekord university, shahrekord mohammad sadraeian pharmaceutical sciences research center, faculty of pharmacy, shiraz university of medical sciences, shiraz, iran hussein honari biology research center, faculty of science, imam hussein university shahram nazarian

background: recombinant vaccine technology is one of the most developed means in controlling infectious diseases. however, an effective vaccine against shigella is still missing. objective: to evaluate recombinant ipac protein of shigella as a vaccine candidate. methods: in this study we cloned ipac gene into an expression vector in prokaryotic system. the protein expression was evaluated by sd...

ژورنال: پژوهش در پزشکی 2006
نژاد مقدم, محمدرضا, چمن‌خواه, محمود, باباشمسی, محمد, مدرسی, سیدمحمدحسین,

Abstract: Background: Streptokinase has been widely prescribed as a fibrinolytic agent for myocardial infarction. Simple structural characteristics of this protein have provided techniques for production of different recombinant types of this protein. The present study was designed to prepare equisimilisH46A subtype of streptokinase in our country. Materials and methods: Having extracted the...

Journal: :Nucleic acids research 1996
E J Cho J B Bae J G Kang J H Roe

The rpoA gene, encoding the alpha subunit of RNA polymerase, was cloned from Streptomyces coelicolor A3(2). It is preceded by rpsK and followed by rplQ, encoding ribosomal proteins S11 and L17, respectively, similar to the gene order in Bacillus subtilis. The rpoA gene specifies a protein of 339 amino acids with deduced molecular mass of 36,510 Da, exhibiting 64.3 and 70.7% similarity over its ...

Journal: :RNA 2010
Aaron R Robart Catherine M O'Connor Kathleen Collins

Telomerase adds simple-sequence repeats to chromosome 3' ends to compensate for the loss of repeats with each round of genome replication. To accomplish this de novo DNA synthesis, telomerase uses a template within its integral RNA component. In addition to providing the template, the telomerase RNA subunit (TER) also harbors nontemplate motifs that contribute to the specialized telomerase cata...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2008
Dirk Hubmacher Ehab I El-Hallous Valentin Nelea Mari T Kaartinen Eunice R Lee Dieter P Reinhardt

Microfibrils are essential elements in elastic and nonelastic tissues contributing to homeostasis and growth factor regulation. Fibrillins form the core of these multicomponent assemblies. Various human genetic disorders, the fibrillinopathies, arise from mutations in fibrillins and are frequently associated with aberrant microfibril assembly. These disorders include Marfan syndrome, Weill-Marc...

Journal: :Protein science : a publication of the Protein Society 2005
Olga V Bocharova Leonid Breydo Vadim V Salnikov Andrew C Gill Ilia V Baskakov

In recent studies, the amyloid form of recombinant prion protein (PrP) encompassing residues 89-230 (rPrP 89-230) produced in vitro induced transmissible prion disease in mice. These studies showed that unlike "classical" PrP(Sc) produced in vivo, the amyloid fibrils generated in vitro were more proteinase-K sensitive. Here we demonstrate that the amyloid form contains a proteinase K-resistant ...

Journal: :The Journal of Experimental Medicine 1994
K Banki E Colombo F Sia D Halladay D H Mattson A H Tatum P T Massa P E Phillips A Perl

Although the etiology of multiple sclerosis (MS) is unknown, there is compelling evidence that its pathogenesis is mediated through the immune system. Molecular mimicry, i.e., crossreactivity between self-antigens and viral proteins, has been implicated in the initiation of autoimmunity and MS. Based on homology to human T cell lymphotropic virus type I (HTLV-I) a novel human retrotransposon wa...

Journal: :The Journal of general virology 2004
Søren U Nielsen Margaret F Bassendine Alastair D Burt Debra J Bevitt Geoffrey L Toms

In the absence of satisfactory cell culture systems for hepatitis C virus (HCV), virtually all that is known about the proteins of the virus has been learned by the study of recombinant proteins. Characterization of virus proteins from patients with HCV has been retarded by the low virus titre in blood and limited availability of infected tissue. Here, the authors have identified a primary infe...

2016
Changliang Hou Jingbo Wang Hua Wu Jiayu Liu Zhiqing Ma Juntao Feng Xing Zhang

COX II containing a dual core CuA active site is one of the three core subunits of mitochondrial Cco, which plays a significant role in the physiological process. In this report, the full-length cDNA of COXII gene was cloned from Sitophilus zeamais, which had an ORF of 684 bp encoding 227 amino acids residues. The predicted COXII protein had a molecular mass of 26.2 kDa with pI value of 6.37, a...

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