A total of 141 cases of strictly defined cerebral malaria were studied in a controlled trial of three regimens: (1) intramuscular artemether plus oral mefloquine, (2) intravenous artesunate plus oral mefloquine, and (3) intravenous quinine (with or without an initial loading dose) plus oral tetracycline. The overall mortalities in each group were 14%, 8.3% and 34.3% respectively. The average pa...

Since its first description in dogs in 1984, the protozoan parasite Neospora caninum has been found to infect a wide range of animals, worldwide. In cattle, N. caninum has particular significance as a cause of abortion in which persistence of infection in the mother, recrudescence of the parasite during pregnancy, and the vulnerability of the placenta and foetus to invasion are important featur...

An 81-year-old male with myasthenia gravis developed a cutaneous infection with Mycobacterium marinum, which apparently resolved following local heat therapy. Five months later, the patient developed new skin lesions and pancytopenia. M. marinum was isolated from his bone marrow. Pulsed-field gel electrophoresis was performed to determine if the skin and bone marrow isolates were clonally relat...

Four patients with progressive visual deterioration were found to have sarcoidosis involving the anterior visual pathway. They all developed chiasmal dysfunction and bilateral optic neuropathy, which responded to megadose corticosteroid therapy. When an attempt was made to withdraw the corticosteroids, the patients experienced a recrudescence of visual dysfunction and were subsequently unable t...

To contribute to the development and evaluation of a practical and cost-effective in vivo testing system for endocrine disruption (specifically environmental estrogens), the effects of 17alpha-ethinylestradiol (EE2) were assessed in a gonadal recrudescence assay with the fathead minnow (Pimephales promelas). Mature male and female fathead minnows were kept first at 15 degrees C on a 8 h light/1...

Abstract Identifying and monitoring the presence of pressurized magma beneath volcanoes allows for improved understanding internal dynamics prediction eruptions. Here we show with time-repeated tomography clear evidence that fresh melts accumulate since 2019 in three reservoirs located at different depths central feeding system. In these volumes, observe a significant reduction seismic wave vel...

L’objectif de cette étude est d’évaluer l’état vulnérabilité des systèmes productions agropastorales face à la variabilité climatique dans le bassin rivière Agbado au centre du Bénin. Ainsi partir chroniques données hydroclimatiques ; statistiques démographiques et planimétriques, méthodes d’analyses climatiques ont été appliquées pour caractériser l’impact sur les agricoles secteur d’étude. L’...