BACKGROUND The guidelines established by the National Comprehensive Cancer Network do not describe mucinous histology as a clinical factor that should influence the therapeutic algorithm. However, previous studies show conflicting results regarding the prognosis of colorectal mucinous adenocarcinoma. In this study, we described the clinicopathological features of mucinous adenocarcinoma in Japa...

Abstract Metastasis pattern of prostate cancer varies widely; however, predominant affinity is towards regional lymph nodes. Mediastinal lymphadenopathy as the initial presentation, in absence any pelvic node involvement, remains extremely rare. Most patients are incidentally diagnosed and often have widespread metastatic disease on confirmation diagnosis. A high index clinical suspicion necess...

AIM AND BACKGROUND Neoadjuvant treatment for rectal adenocarcinoma improves local control and represents the standard for locally advanced disease. Laparoscopic and robotic total mesorectal excision has been increasingly adopted. It provides magnified visualization of the pelvic cavity, thereby facilitating the mesorectal dissection. METHODS Consecutive patients with locally advanced/ultralow...

BACKGROUND & AIMS The purpose of this prospective observational study was to evaluate the rate and the prognostic factors for down-staging and complete response for rectal adenocarcinoma after induction chemotherapy and neoadjuvant chemoradiation followed by surgery, and to analyze the rate of sphincter-saving surgery. METHODS We included from March 2011 to October 2013 a number of 88 patient...

INTRODUCTION Isolated vaginal metastases from colorectal cancer are extremely rare. There are only a few reported cases in the English literature, and the characteristics of such cases of metastasis remain relatively unknown. PRESENTATION OF CASE We present a case of isolated vaginal metastasis from rectal cancer in a 78-year-old female patient. The patient had no symptoms related to vaginal ...

Abstract Background Primary signet-ring cell carcinoma (SRCC) of the prostate is a rare and aggressive subtype adenocarcinoma with poor prognosis, only approximately 60 cases reported worldwide. Case presentation A 62-year-old man presented acute urinary retention hematuria, after year’s history lower tract symptoms. Digital rectal examination revealed an irregular hard prostate. Flexible cysto...

Serious complications have not been previously reported during seed implantation for prostate brachytherapy. We present an unreported case of rectal injury caused by an ultrasound probe. A 67-year-old male presented with a serum prostate-specific antigen level of 5.50 ng/ml, a Gleason score of 7 (3 + 4) and clinical T2a adenocarcinoma of the prostate. A transperineal permanent prostate brachyth...

BACKGROUND The relationship between radiation exposure for treatment of cancer and occurrence of a second primary cancer at the irradiated site is well known. This phenomenon is however rare in prostate. CASE PRESENTATION A 75-year-old farmer was treated for rectal cancer with preoperative 45 Gy of radiotherapy and abdominoperineal resection. Four years later he developed symptoms of bladder ...

Introduction: Solitary rectal ulcer syndrome (SRUS) is a great masquerader and misdiagnosis has serious implications for the patient. Methods and materials: We reviewed 21 patients with histopathologically proven SRUS at our tertiary care teaching hospital in South India. Results: Bleeding per rectum and constipation with passage of mucous were the common symptoms at presentation. Endoscopy rev...