Background: The role of apolipoprotien E polymorphisms do not diagnostic correctly in recurrent pregnancy loss etiology but Apo E has been shown to play an important role in lipid metabolism in pregnancy. We evaluated these polymorphisms in Iranian women with unexplained recurrent pregnancy loss. Materials and Methods: 5 ml Blood were sampling from 81 women with a history of two or more consecu...

Zusammenfassung 1 bis 3 % aller Paare im fortpflanzungsfähigen Alter erleiden einen wiederholten Spontanabort (WSA). Es werden viele ursächliche Faktoren diskutiert, doch bleibt die Ursache in einem erheblichen Teil der Fälle ungeklärt. Die wissenschaftliche Datenlage hinsichtlich Diagnose- und Behandlungsstrategien ist nach wie vor unzureichend, was für oftmals eine psychische Belastung Ärztin...

Abstract Study question How does the Positive Reappraisal Coping Intervention (PRCI) sustain coping during early stages of a new pregnancy in women with recurrent loss (RPL)? Summary answer The PRCI improved psychological well being by sustaining and providing respite from stress uncertainty. What is known already Increased levels maternal anxiety uncertainty are common following RPL when wait ...

background: mitochondrial transfer rnas (trna) genes are essential components of protein biosynthesis. these genes are hotspots for mutations. these mutations are associated with a wide spectrum of human disease. many genetic factors are known in assessment of repeated pregnancy loss (rpl). objective: the aim of this study was analysis of trna thr and trna pro in women with rpl. materials and m...

Background: Protein C deficiency is a rare disease; it could be primary or secondary. Female patients with protein may develop pregnancy-associated thrombosis. The clear association between the and fertility in-vitro fertilization (IVF) results has not been known yet. In our study, we aimed to determine prevalence of in Syrian infertile women assess impact on abortion, recurrent IVF Failure, re...

Background: Mitochondrial transfer RNAs (tRNA) genes are essential components of protein biosynthesis. These genes are hotspots for mutations. These mutations are associated with a wide spectrum of human disease. Many genetic factors are known in assessment of repeated pregnancy loss (RPL). Objective: The aim of this study was analysis of tRNA Thr and tRNA Pro in women with RPL. Materials and M...

Background: The aetiology of recurrent pregnancy loss (RPL) is varied and ranges from genetic abnormalities, autoimmune, uterine structural thrombophilic disorders, endocrinologic dysfunction, infective to idiopathic factors. Reproductive immunology may provide an area opportunity in treatment cases. Research has indicated that any amount HLA compatibility among spouses leads immunological pert...

Sudden sensorineural hearing loss (SSNHL) is usually unilateral and can be associated with tinnitus and vertigo. The most common causes of this disease are known to be the vascular and viral agents, but immune disorders are involved in the development of sudden deafness. The antiphospholipid syndrome (APS) is an acquired autoimmune system disorder, which is defined as the presence of antiphosph...

Abstract Study question To what extent do genomic variants contribute to idiopathic recurrent pregnancy loss (RPL)? Summary answer Pathogenic uniparental disomy, copy number variations, and single nucleotide were identified in 18 of 83 couples their embryos/fetuses with RPL. What is known already RPL defined as the two or more pregnancies before 24 weeks gestation. The etiologies include antiph...