currently, hematopoietic stem cell transplantation (hsct) is the only curative option for patients with beta-thalassemia major, but liver iron overload in these patients will not decrease and hepatic fibrosis may still progress despite successful hsct. liver biopsy samples were taken from 14 patients (out of 25 patients) who underwent hsct. all patients met three criteria: negative hcv antibody...

background: a case-control study was carried out to investigate the roles of prior allergies and family history of cancers and their interaction in the etiology of adult leukemia. methods: prior allergies status and family history of cancers in first-degree relatives were compared between 131 incident leukemia cases and 206 hospital-based controls. odds ratios (or) were estimated using an uncon...

BACKGROUND Patients' informed consent is legally essential before elective invasive cardiac angiography (CA) and successive intervention can be done. It is unknown to what extent patients can remember previous detailed information given by a specially trained doctor in an optimal scenario as compared to standard care. METHODOLOGY/PRINCIPAL FINDINGS In this prospective cohort study 150 consecu...

Background: Patient autonomy in the health care system is achieved by vital principle of providing informed consent. Throughout history, consent gained recognition and improved to include more aids steps formalize standardize process obtaining proper medical dental practice. Regardless type obtained before treatment, it should an adequate understandable description nature diagnosis disease, tre...

OBJECTIVE To evaluate differences between adults who consent to participate in observational research and those who do not. DESIGN Prospective, population-based cohort study. SETTING 35 randomised Irish general practices. PARTICIPANTS 1609 adults with ischaemic heart disease identified in 2000-1. INTERVENTION Medical records search, postal questionnaire and consent form in 2005-6. MAI...

INTRODUCTION Prospective informed consent is required for most research involving human participants; however, this is impracticable under some circumstances. The Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans (TCPS) outlines the requirements for research involving human participants in Canada. The need for an exception to consent (deferred consent) is recognised an...

Two types of legislation underlie cadaveric organ donations: presumed consent (PC) and informed consent (IC). In informed consent countries, people are only donors when deceased if they registered to do so while alive. Conversely, in presumed consent countries, anybody is a potential donor when deceased. People have thus to register if they do not want to donate their body. PC has always been p...

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