BACKGROUND Hair dye products constitute an important source of allergen exposure, and contribute importantly to allergic contact dermatitis in consumers and hairdressers. OBJECTIVES To evaluate the presence of potent contact sensitizers in oxidative hair dye products intended for home use on the US market. METHODS Ingredient labels of 107 hair dyes from 10 major brands were examined and use...

Henna stone is a lesser-known commercially available material used to obtain black henna paste (1). In some countries, including Turkey, local herb sellers sell it as ‘natural stone’, a so-called natural source for black henna. The stone has to be crushed into powder first, and then mixed with water, hydrogen peroxide and, sometimes, natural henna to obtain black henna paste for the purpose of ...

N,N-didecyl-N-methyl-poly(oxyethyl) ammonium propionate is a quaternary ammonium compound that is used to disinfect medical devices. Occupational allergic contact dermatitis caused by quaternary ammonium compounds in healthcare workers is an increasingly important issue (1). We report a case of severe allergic contact dermatitis caused by N,N-didecyl-N-methyl-poly(oxyethyl) ammonium propionate ...

BACKGROUND This is the first randomized, double-blind, placebo-controlled trial (EUDRACT No. 2009-013923-43) evaluating nickel oral hyposensitizing treatment (NiOHT) in patients with "systemic nickel allergy syndrome" (SNAS), characterized by Ni-allergic contact dermatitis and systemic reactions after eating Ni-rich food. METHODS Adults with positive Ni-patch test, who reported symptoms sugge...

BACKGROUND Currently, cosmetic series (Chemotechnique Diagnostics, Sweden) is the most widely used cosmetic-related patch test in Korea. However, no studies have been conducted on how accurately it reflects the constituents of the cosmetics in Korea. OBJECTIVE We surveyed the constituents of various cosmetics and compare with the cosmetic series, to investigate whether it is accurate in deter...

This paper describes the development and significance of online systems for the collection and analysis of medical data (patch test results) with a web application. Modern digital tools greatly aid in collecting, combining, and preserving the data in a way that is friendly, undemanding and time-efficient for the dermatologist. Creating a central database for the results of patch testing provide...

Methylisothiazolinone (MI) (CAS no. 2682-20-4) and methylchloroisothiazolinone (MCI) (CAS no. 26172-55-4) have been widely used as preservatives in cosmetics, household products and industrial products since the late 1970s. The first cases of contact allergy to the MCI/MI combination were noted in 1980 (1). Ironing water is being increasing used as a product designed to making ironing more enjo...

Nickel allergic contact dermatitis (ACD) has become a more widely recognized disease process over the last three decades in the United States. A subpopulation of ACD patients will manifest with systemic contact dermatitis (SCD). Specifically, those cases of widespread recalcitrant nickel ACD with only partial clinical relief after strict nickel avoidance, suggest SCD. Evidence indicates that ap...

Epoxy resins, widely used as adhesives or coatings in construction, boat and aeroplane building, plastic and other industries and trades (1–3), are a frequent cause of occupational allergic contact dermatitis (1–6). Epoxy resin based on diglycidylether of bisphenol A is the main allergen responsible but sensitization can also develop to other components, including the hardeners and reactive dil...