Free radical generation plays a key role in killing bacteria by antibiotics. However, radicals are short-lived and reactive, thus difficult to detect for the state of art. Here we use technique which allows optical nanoscale magnetic resonance imaging (MRI) on scale single bacteria. We demonstrate that Staphylococcus aureus increases presence UV irradiation as well vancomycin is dependent antib...

PURPOSE Voxel-based relaxometry (VBR) is a technique in which a voxel-level statistical comparison of quantitative MR T2 maps is performed to identify regions with significantly elevated T2 relaxation time. Our objective was to assess the performance of single-subject VBR at 3T as a diagnostic tool for patients whose diagnosis of epilepsy or seizure focus location is uncertain. METHODS Fifty-...

PURPOSE To establish normal age-related changes in the magnetic resonance (MR) T(2) relaxation time constants of brain using data collected as part of the National Institutes of Health (NIH) MRI Study of Normal Brain Development. MATERIALS AND METHODS This multicenter study of normal brain and behavior development provides both longitudinal and cross-sectional data, and has enabled us to inve...

A comprehensive tract-based characterisation of white matter should include the ability to quantify myelin and axonal attributes irrespective of the complexity of fibre organisation within the voxel. Recently, a new experimental framework that combines inversion recovery and diffusion MRI, called inversion recovery diffusion tensor imaging (IR-DTI), was introduced and applied in an animal study...

Introduction Previous studies suggested that susceptibility to schizophrenia is based at least to some extent on genes [1]. However, evolution of the disease is believed to depend on interaction between the genetic factors and physical, psychological and psychosocial factors, which have not been completely described yet [2]. To distinguish between the morphologic and metabolic changes in the br...

INTRODUCTION Deep brain stimulation (DBS) nowadays is a well-established treatment of motor symptoms in Parkinson's disease. The subthalamic nucleus (STN) is a common target for DBS, because motor improvements have been shown to be superior to best medical therapy, if DBS electrodes have been appropriately positioned. DBS target identification can be assisted by MRI beyond structural imaging by...