Genetically modified mouse models with defects in DNA repair pathways, especially in nucleotide excision repair (NER) and mismatch repair (MMR), are powerful tools to study processes like carcinogenesis and mutagenesis. The use of mutant mice in these studies has many advantages over using normal wild type mice with respect to costs, number of animals, predictive value towards carcinogenic comp...

introduction : although many techniques have been described for reconstruction of the giant omphalocele, we present a simple , effective and safe new technique. materials and methods: we have studied 11 neonates with giant omphalocele that were treated by a new technique, umbrella repair, in sarvar pediatric hospital of mashhad, iran. in this new technique we released the skin around the omphal...

objective: different ceramic repair systems have been reported for fractured ceramics. however, limited information is available concerning the bond strength of these systems especially after thermocycling. the aim of this in-vitro study was to determine the effect of thermocycling on the shear bond strength of composite-resin to feldspathic porcelain with and without silane pretreatment. mater...

statement of problem: in some clinical situations, repair of composite restorations is treatment of choice. improving the bond strength between one new and old composite usually requires increased surface roughness to promote mechanical interlocking since chemical bonding might not be adequate. similarly, the treatment of a laboratory fabricated resin composite restoration involves the same pro...

patients and methods previously recorded data of 231 patients who underwent surgical closure of vsd between january 2009 and january 2012 at the rajaie cardiovascular medical and research center were retrospectively reviewed. vsd surgical repair was performed using continues suturing technique in group a patients (n = 163, 70.6%) and interrupted suturing technique in group b patients (n = 68, 2...

the management of machine replacement (specifically tractors) is one of the most critical factors for performing field operations on time. therefore, tractor repair and maintenance costs must be accurately predicted. this research was carried out to evaluate the use of the regression technique in predicting tractor repair and maintenance costs. the study was conducted using empirical data on 60...

BACKGROUND Urgent or emergent status is often associated with increased risk among cardiac operations. The objective of this study was to analyze outcomes and cost differences in patients undergoing elective versus urgent or emergent mitral valve replacement (MVR) and repair operations. METHODS From 2003 to 2008, 1,477 patients underwent isolated, primary mitral valve (MV) operations at 11 di...

Background: This study compared acute Achilles tendon repairs' functional and clinical outcomes with two different surgical techniques; modified percutaneous open repair.
 Material Method: retrospective analyzed 57 patients an rupture (AATR) who underwent repair. 46 met the eligibility criteria were enrolled divided into groups based on technique. 23 from Group 1 treated using repair under...

The ideal timing for repair of CAVC malformations remains controversial. Some authors advocate primary repair at the age of six months or earlier before the onset of irreversible pulmonary hypertension especially in the presence of Down syndrome. Others suggest two-stage repair consisting of pulmonary artery banding as a first stage followed by complete repair thereafter. The aim of this work w...