The tetrameric Lac repressor can bind simultaneously to two lac operators on the same DNA molecule, thereby including the formation of a DNA loop. We investigated the phasing dependence of DNA loop formation between lac operator O1 and an auxiliary ideal lac operator (O(id)) on the bacterial chromosome, with inter-operator distances varying from 57.5 to 1493.5 bp. Repression of a CAP-independen...

A transient transfection assay using Drosophila S2 tissue culture cells and WT and mutant Drosophila vnd/NK-2 homeobox cDNAs was used to localize repression and activation domains of vnd/NK-2 homeodomain protein. A repression domain was identified near the N terminus of vnd/NK-2 homeodomain protein (amino acid residues 154-193), which contains many hydrophobic amino acid residues. The major det...

We build a model for predicting civil wars where the government bargains with an opposition group using concessions and repression. The equilibrium is either a state of perpetual peace where there are only concessions and no repression, or the equilibrium leads to civil wars, where the concessions are lower and repression higher as compared to the peace equilibrium. An initial movement towards ...

Aux/IAA proteins are short-lived nuclear proteins that repress expression of primary/early auxin response genes in protoplast transfection assays. Repression is thought to result from Aux/IAA proteins dimerizing with auxin response factor (ARF) transcriptional activators that reside on auxin-responsive promoter elements, referred to as AuxREs. Most Aux/IAA proteins contain four conserved domain...

CD43 is an abundant, heavily glycosylated molecule expressed specifically on the surface of leukocytes and platelets. When leukocytes are at rest, CD43 acts to prevent both homotypic and heterotypic interactions. However, during leukocyte activation CD43 expression is repressed, facilitating the intercellular contact required for chemotaxis, phagocytosis, aggregation, adhesion to endothelium, a...

Cyclic adenosine 3’,5’-monophosphate (cyclic AMP) increases the differential rate of synthesis of @-galactosidase in Escherichia coli made permeable by treatment with t&(hydroxymethyl)aminomethane and ethylenediaminetetraacetic acid. In normal, growing cells, cyclic AMP overcomes the transient repression of /3-galactosidase by glucose. A half-maximal effect of cyclic AMP occurs at about 7 x 10-...

There is the general perception that media repression in Philippines, at its worst, happened only during Martial Law years from 1972 to 1986.Indeed, was time when almost all...

Cyclic adenosine 3’,5’-monophosphate (cyclic AMP) increases the differential rate of synthesis of @-galactosidase in Escherichia coli made permeable by treatment with t&(hydroxymethyl)aminomethane and ethylenediaminetetraacetic acid. In normal, growing cells, cyclic AMP overcomes the transient repression of /3-galactosidase by glucose. A half-maximal effect of cyclic AMP occurs at about 7 x 10-...

This article studies the problem faced by activists who want to maximize firms’ compliance with high environmental standards. Our focus is on radical activism which relies non-violent civil disobedience. The threat of disruptive actions used force firms concede, i.e., engage in self-regulation. We adopt a mechanism design approach characterize an optimal campaign. analysis indicates that least ...