Whereas cells productively infected with human immunodeficiency virus type 1 (HIV-1) decay rapidly in the setting of highly active antiretroviral therapy (HAART), latently infected resting CD4(+) T cells decay very slowly, persisting for the lifetime of the patient and thus forming a stable reservoir for HIV-1. It has been suggested that the stability of the latent reservoir is due to low-level...

BACKGROUND In the setting of highly active antiretroviral therapy (HAART), plasma levels of human immunodeficiency type-1 (HIV-1) rapidly decay to below the limit of detection of standard clinical assays. However, reactivation of remaining latently infected memory CD4+ T cells is a source of continued virus production, forcing patients to remain on HAART despite clinically undetectable viral lo...

A prerequisite for accurate dating by means of carbon-14 is the existence of a steady state in the specific activity of the carbon in the atmosphere. The studies1 which have been made of carbon activity supported the view that there was a state of dynamic equilibrium in the carbon exchange between natural reservoirs. A disturbance in this state is known to arise from the discharge of the combus...

History matching is the process of updating a petroleum reservoir model using production data. It is a required step before a reservoir model is accepted for forecasting production. The process is normally carried out by flow simulation, which is very time-consuming. As a result, only a small number of simulation runs are conducted and the history matching results are normally unsatisfactory. I...

Reservoir modeling is a critical step in the planning and development of oil fields. Before a reservoir model can be accepted for forecasting future production, the model has to be updated with historical production data. This process is called history matching. History matching requires computer flow simulation, which is very time-consuming. As a result, only a small number of simulation runs ...

~BSTRACT: A~ unsteady ~wo-dimens~onal (20) reservoir hydrodynamics and transport model is employed to slm~late contammate~ denSity cu~ents m the Shasta Reservoir after a chemical spill into the Sacramento River, Cahf. Three flow regimes (plungmg flow, underflow, and interflow) and their occurrence are captured by the laterally ~verag~d model. Transp~~ and mixing processes in the temperature-str...

for the characteristics of horizontal fractures in shallow low-permeability oil layers after hydraulic fracturing in multilayer reservoirs, horizontal fractures are taken equivalent to an elliptical cylinder with the reservoir thickness using the equivalent permeability model; then, upon the elliptic seepage theory, the seepage field which has led by a vertical well with horizontal fractures is...

The mixed linear programming model is commonly recognized to be an effective means for searching optimal reservoir operation policy in water resources system. In this paper a multi-objective mixed integer linear programming model is set up to obtain the optimal operation policy of multi-reservoir water supply system during drought, which is able to consider the operation rule of reservoir-group...

This paper examines the validity of a recently introduced reservoir simulation and modeling technique. The technique, that is named Top-Down Intelligent Reservoir Modeling, TDIRM (not to be confused with BP’s TDRM history matching technique), integrates traditional reservoir engineering analysis with Artificial Intelligence & Data Mining (AI&DM) technology in order to arrive at a full field mod...

This paper proposes a novel history matching method where reservoir structure is inverted from dynamic fluid flow response. The proposed workflow consists of searching for models that match production history from a large set of prior structural model realizations. This prior set represents the reservoir structural uncertainty due to interpretation uncertainty on seismic sections. To make such ...