DELLA proteins, consisting of GA INSENSITIVE, REPRESSOR OF GA1-3, RGA-LIKE1 (RGL1), RGL2, and RGL3, are central repressors of gibberellin (GA) responses, but their molecular functions are not fully understood. We isolated four DELLA-interacting RING domain proteins, previously designated as BOTRYTIS SUSCEPTIBLE1 INTERACTOR (BOI), BOI-RELATED GENE1 (BRG1), BRG2, and BRG3 (collectively referred t...

Helicobacter Pylori (H. pylori) as a gram-negative bacterium is the most common infection of the gastrointestinal tract, and worldwide it affects the children over three years of age. H. pylori could cause gastrointestinal and extra-intestinal manifestations. Antibiotic resistance can happen primarily and occurs during treatment. We aimed to evaluate the resistance gene of H. pylori obtained fr...

Diverse molecular networks underlying plant growth and development are rapidly being uncovered. Integrating these data into the spatial and temporal context of dynamic organ growth remains a technical challenge. We developed 3DCellAtlas, an integrative computational pipeline that semiautomatically identifies cell types and quantifies both 3D cellular anisotropy and reporter abundance at single-...

background: pfmdr1 and its variants are molecular marker which are responsible for antibiotics resistance in plasmodium falciparum, a parasitic carrier for malaria dis-ease. a novel strategy to treat malaria disease is by disrupting parasite lactate dehy-drogenase (pldh), a crucial enzyme for plasmodium survival during their erythro-cytic stages. this research was aimed to investigate and chara...

background pseudomonas aeruginosa is a leading cause of infections especially in patients with weakened immune systems. this pathogen is intrinsically resistant to many antibacterial agents. objectives the aim of this study was to survey the antibiotic resistance pattern and frequency of bla oxa10 gene in carbapenemase producing p. aeruginosa isolated from patients in isfahan hospitals. materia...

background: chemotherapy plays a very important role in the treatment of leukemia but the resistance properties of the lymphoblasts limit the effect of chemotherapy. one of the main mechanisms of resistance to chemotherapy is the increased expression of mdr1 gene. the aim of this study was to explore the effect of resveratrol on the expression of mdr1 gene in leukemic lymphoblast of new cases o...

Systemic acquired resistance (SAR) is a broad-spectrum resistance mechanism in plants that is activated in naive organs after exposure of another organ to a necrotizing pathogen. The organs manifesting SAR exhibit an increase in levels of salicylic acid (SA) and expression of the PATHOGENESIS-RELATED1 (PR1) gene. SA signaling is required for the manifestation of SAR. We demonstrate here that th...

Biodiesel is touted to be an alternative the fossil fuels as it conducive environment. This investigation proposes a control framework produce biodiesel in reactive distillation column via transesterification process. To extract quality product, temperature profile must maintained along per requirements. However, constant interactions among products inside disturb and consequently product quali...