The in vivo activities of daptomycin, fosfomycin, and a combination of both antibiotics against a clinical isolate of methicillin-resistant Staphylococcus aureus (daptomycin MIC, 0.25 μg/ml; fosfomycin MIC, 0.5 μg/ml) were evaluated in a rat model of osteomyelitis. A total of 37 rats with experimental osteomyelitis were treated for 4 weeks with either 60 mg/kg of body weight of daptomycin subcu...

Post operative wound infections have been found to pose a major problem in the field of surgery. Advances in control of infection have not completely eradicated this problem because of development of drug reistance. The present study was carried out in Index Medical College hospital, one year study. 100 patients were recruited who underwent surgery in the orthopedic, obstetrics and gynecology a...

Staphylococcus aureus is opportunistic human as well as animal pathogen that causes a variety of diseases. A total of 100 Staphylococcus aureus isolates were obtained from clinical samples derived from hospitalized patients. The presumptive Staphylococcus aureus clinical isolates were identified phenotypically by different biochemical tests. Molecular identification was done by PCR using specie...

BACKGROUND AND OBJECTIVE The prevalence of community acquired methicillin resistant Staphylococcus aureus (CA-MRSA) is increasing around the world. It involves healthy people and causes a variety of diseases. MATERIAL AND METHODS This cross sectional study was conducted from September 2010-June 2011 on children less than 14 years of Ahvaz, southwest Iran. The participants were selected with t...

The purpose of this study was to determine the antibacterial activity of ten essential oils. The ten essential oils were tested on MRSA and MSSA from hospital patients using the disk diffusion (Kirby Bauer) method. Based on this study, all ten oils showed higher effectiveness inhibiting MRSA and MSSA growth than vancomycin, which is the currently used standard for treatment. Essential oils coul...

Bovine mastitis caused by multidrug resistant Staphylococcus aureus is a huge problem reported worldwide, resulting in prolonged antibiotic treatment and death of livestock. The current study is focused on surveillance of antibiotic susceptibility along with genotypic and phenotypic characterization of the pathogenic S. aureus strains causing mastitis in India. One hundred and sixty seven milk ...

LEARNING OBJECTIVES : After studying this article, the participant should be able to: 1. Identify risk factors associated with community-acquired methicillin-resistant Staphylococcus aureus. 2. Recognize the clinical presentation of patients with community-acquired methicillin-resistant S. aureus. 3. Understand the treatment and indications for decolonization of patients who have community-acqu...

BAL0030543, BAL0030544, and BAL0030545 are dihydrophthalazine inhibitors with in vitro potency against gram-positive pathogens. The MIC(50)s for methicillin (meticillin)-sensitive Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, hetero-vancomycin-resistant Staphylococcus aureus, and vancomycin-resistant Staphylococcus aureus (VISA) range from 0.015 to 0.25 microg/ml (MIC(90)s...

this study was carried out to find the extent of staphylococcal carriages including methicillin resistant staphylococcus aureus mrsa in employee's of teaching university hospitals in yazd. nasal swabs of 742 employees in four different medical teaching hospitals in yazd were collected, and tested for detection of staphylococci strains. out of 742 employees, 94 (12.7%) were carrier of staphyloco...

Antibiotic-Resistant Pattern and Multiple Antibiotic Index of Multidrug-Resistant Staphylococcus aureus from Wound Infection Patients in a Tertiary Institution South Eastern Nigeria