Inadequate intensity of the polymerization light source can compromise the quality and longevity of dental composite restorations. In order to maintain optimal strength of polymerization devices, regular control of polymerization units is necessary. The aim of this study was to compare the accuracy of two radiometers in the measurement of light intensity of photopolymerization devices concernin...

We have investigated the performance evaluation of different Hybrid Optical Amplifiers (EDFA-SOA, RamanSOA, Raman-EDFA) .The proposed configuration consists of 64, 96 and 128 channels at speed of 10 Gbps. We have realized the different hybrid amplifiers and their parameters like BER, Output Power at different numbers of channels. The different can provide better result and better feasibility fo...

Lethal effects of zinc sulphate (ZnSO4.H2O), a widespread environmental pollutant was evaluated following exposure at different concentrations of the toxicant to Tilapia species, Oreochromis niloticus based on toxicity index of 96 hrs LC50 values. The obtained results were analyzed by the Finney’s Probit Analysis LC50 Method and 96 hrs LC50 value for Oreochromis niloticus was found to be 72.431...

Figure. Colorectal cancer burden and access to primary health care, California. A vast majority of Californians (96%) live within a 30-minute drive of a federally qualified health center (FQHC). This is true for areas in both the top and bottom quintiles (96% and 93% respectively) based on the percentage of colorectal cancers (CRC) diagnosed at a late stage. There was no meaningful connection f...

KRAS, NRAS and BRAFV600E mutations determine resistance to anti-epidermal growth factor receptor (EGFR) monoclonal antibodies in patients with metastatic colorectal cancer (mCRC). The phase II CAPRI 2-GOIM trial investigates the efficacy safety of biomarker-driven, cetuximab-based therapies three sequential treatment lines mCRC patients. Patients RAS/BRAFV600E wild type (WT) mCRC, as determined...

Vaginally delivered microbicides are being developed to offer women self-initiated protection against transmission of sexually transmitted infections such as Chlamydia trachomatis. A small molecule, DS-96, rationally designed for high affinity to Escherichia coli lipid A, was previously demonstrated to bind and neutralize lipopolysaccharide (LPS) from a wide variety of Gram-negative bacteria (D...

Chagas disease is caused by infection with the insect-transmitted protozoan Trypanosoma cruzi, and is the most important parasitic infection in Latin America. The current drugs, benznidazole and nifurtimox, are characterized by limited efficacy and toxic side-effects, and treatment failures are frequently observed. The urgent need for new therapeutic approaches is being met by a combined effort...