BACKGROUND Single-nucleotide polymorphisms in the promoter region of the FAS and FASLG may alter the transcriptional activity of these genes. We therefore investigated the association between the FAS and FASLG polymorphisms and risk for second primary malignancy (SPM) after index squamous cell carcinoma of the head and neck (SCCHN). METHODS We used log-rank test and Cox proportional hazard mo...

abstract: genotyping of the hepatitis c virus (hcv) is important for designing therapeutic strategies and regional specific diagnostic assays. the aim of this study was to identify the hcv genotypes in hcv infected blood donors. this is the first report on hcv genotypes in blood donors in iran. in this cross-sectional study, 103 blood donors with hepatitis c were investigated for hcv genotypes....

To investigate whether the effect of the calcimimetic AMG 641 and calcitriol on CaSR and VDR expression could be separated from their ability to reduce parathyroid cell proliferation, five-sixth nephrectomized (5/6 Nx) rats received vehicle, AMG 641, calcitriol, or AMG 641+calcitriol either daily for 13 days (long-term protocol) or in a single dose (short-term protocol). In the long-term protoc...

In this study, the effect of quenching and partitioning (Q&P) heat treatment on structural mechanical properties AISI 4130 steel was investigated. The Q&P process followed at a quench temperature 270 oC three different temperatures 270, 330, 380 oC. phase characterization prepared spicimens were done using X-ray diffractometer (XRD) scanning electron microscopy (SEM), respectively. samples also...

There is not much information available regarding the prevalence of the genotypes of Helicobacter pylori isolates in Turkey, particularly in eastern Turkey. The aims of this study were to detect the prevalence of different genotypes of H. pylori in Turkish patients with gastrointestinal complaints and to determine the relationship of these genotypes with clinical outcome and sex. One hundred fo...

An appropriate dose of radiation should be established on target genotypes before large scale mutagenesis undertaken. The objective of this study was to determine an ideal dose of gamma radiation to induce genetic variation in selected cowpea (Vigna unguiculata) genotypes. Seeds of three Namibian released cowpea genotypes were gamma irradiated using seven dozes at the International Atomic Energ...

The objective of this study was to evaluate the effect aluminum and mitigating potential H2O2 on stress antioxidant responses in canola (Brassica napus var. oleifera (Moench) Delile) affecting emergence initial growth plants. Canola seeds, cultivar Hyola 61, were treated with different concentrations solution (0.0, 0.075, 0.15 M), later sown under 10, 20, 30 mmolc dm-3). After 20 days plant eme...

Although controversial, diminished activity of 5,10 methylenetetrahydrofolate reductase (MTHFR), a regulatory enzyme of homocysteine metabolism, may predispose to migraine in Turkish people. In a case-control study, we determined the prevalence of two common MTHFR polymorphisms,C677T and A1298C, in 102 migraine patients (23 migraine with aura, 70 migraine without aura and nine with tension-type...