There aren’t many problems in biology that have remained unsolved for over a century. Yet one of these problems, the scaling of resting metabolic rates in animals with their body mass, has not only evaded solution but has even evaded description! The problem is simple, how does the amount of energy an animal uses at rest change with its size? The answer may seem obvious – a resting mouse uses l...

&AINSBY, WENDELL N. Azltoregulation of blood flow in skeletal muscle during increased metabolic activity. Am. J. Physiol. 202(2) : 273-276. 1962. -The effect of increased metabolic rate on autoregulation of blood flow in skeletal muscle was investigated by stimulating muscle to contract. At elevated metabolic rates good autoregulation of blood flow was observed but at higher blood flow levels t...

Exercise training is generally a healthful activity and an effective intervention for reducing the risk of numerous chronic diseases including cardiovascular disease and diabetes. This is likely both a result of prevention of weight gain over time and direct effects of exercise on metabolism of lipids and the other macronutrient classes. Importantly, a single bout of exercise can alter lipid me...

The purpose of this investigation was to determine whether differences in body composition, pharmacological treatment, and physical activity explain the increased resting metabolic rate (RMR) impaired insulin sensitivity hypertension. Resting blood pressure, RMR (indirect calorimetry), composition (dual-energy X-ray absorptiometry), (accelerometry), maximal oxygen uptake (VO2max) (ergospirometr...

OBJECTIVE To assess changes in body composition, body weight and resting metabolic rate in patients who received intrathecal baclofen therapy for spasticity. DESIGN Prospective, longitudinal, quasi-experimental, with a pre/post design. PATIENTS Twelve patients with spasticity, fulfilling study criteria, and due for pump implantation for intrathecal baclofen therapy, completed the study. M...