Restless legs syndrome (RLS) is a common condition that is frequently unrecognized, misdiagnosed and poorly managed. It is characterized by uncomfortable sensations deep in the legs developing at rest that compel the person to move; symptoms are worst at night and sleep disturbance is common. RLS occurs in 7%-11% of the population in Western countries, and many such people experience troublesom...

OBJECTIVE There are no data adressing the prevalence of restless legs syndrome in subjects who have knee prosthesis. Therefore, we conducted a cross-sectional survey of subjects who underwent knee prosthesis surgery. METHOD A total of 107 subjects (30 male, 77 female) were interviewed over the telephone regarding restless legs syndrome symptoms. If the patients exhibited symptoms of the syndr...

BACKGROUND Restless Legs Syndrome is very common in hemodialysis patients however there are no comparative studies assessing the effectiveness of a non-pharmacological treatment to a classical treatment on parameters related to syndromes' severity and quality of life. METHODS In this randomized, partially double blind, placebo controlled trial, thirty two hemodialysis patients with restless l...

BACKGROUND Restless leg syndrome (RLS) is defined as an uncomfortable feeling in the limbs which is prominently sensed in legs. Dopamine system involvement is considered as the base of RLS's etiology. Because of safety, anti-oxidant and dopaminergic promoting action of selenium, this study aims to investigate the effect of selenium on restless leg syndrome treatment. METHODS Sixty patients wi...

Restless legs syndrome (RLS) is a common neurological disorder characterized by an irresistible urge to move the legs at night, which is often accompanied by unpleasant sensations. A recent genomewide association study identified an association between RLS and intronic markers from the MEIS1 gene. Comparative genomic analysis indicates that MEIS1 is the only gene encompassed in this evolutionar...

The aim of this case report is to report a case of restless legs syndrome (RLS) in a patient with bipolar disorder (BD) caused by olanzapine and to draw attention to possible relationship between BD and RLS. A female patient was diagnosed with mixed episode of BD. Olanzapine 10 mg/day was added to the extended release valproic acid 1000 mg/d treatment that the patient was using. In the next day...

Introduction: Pregnancy is associated with significant physiological, psychological, and social changes that affect normal sleep. Sleep disorders whose frequency increases significantly during pregnancy can include restless legs syndrome (RLS). The incidence of RLS in gestational age reaches its maximum the third trimester pregnancy. Reduced sleep quality hypertension pre-eclampsia (PE), among ...

Restless Legs Syndrome (RLS) is a common disorder. In its mild, intermittent form it can affect up to 15% of the general population. Approximately 3% may develop clinically significant disease affecting daytime functioning and sleep. RLS is more frequent in women and during pregnancy. It can affect children and the elderly. These special populations are rarely if at all included or reported in ...

OBJECTIVE To describe the diagnostic features of a patient who presented to a chiropractor with restless legs syndrome (RLS), a common but often under-diagnosed condition. CLINICAL FEATURES A 42-year-old male patient presented with twitching and deep pressure in the legs bilaterally; described also as an uncomfortable urge to move the legs that followed a circadian rhythm occurring in the eve...

BACKGROUND Sleep is one of the most fundamental human needs; without any doubt sleep is even more essential for sick patients, especially for patients with chronic illnesses. Sleep disturbance may lead to anxiety and reduced quality of life. Restless leg syndrome (RLS) is a sensory-motor disorder accompanied by a strong desire to move the legs or other parts of the body, which can cause sleep d...