PURPOSE To evaluate the alterations in the retinal nerve fiber layer in diabetic retinopathy treated by argon laser panphotocoagulation. METHODS Prospective study of patients with diabetic retinopathy submitted to retinal panphotocoagulation. Initially, complete ophthalmologic examination and optical coherence tomography were performed. All patients were submitted to panphotocoagulation with ...

Vigabatrin is an effective antiepileptic drug (AED) typically used in the treatment of refractory partial seizures and infantile spasms. Its use, however, is limited due to the concern of retinal toxicity and subsequent visual field defects. Herewith in we describe a case of vigabatrin toxicity that illustrates electroretinographic (ERG) changes occur before imaging and visual field deteriorati...

Dear Editor, I read with interest the recently published article titled " Unilateral Myelinated Retinal Nerve Fiber Layer Associated with Axial Myopia, Amblyopia and Strabismus " by Moradian and Karimi. 1 I would like to share my experience with two similar cases. Case 1: A 4 year-old girl was referred because of refractory amblyopia in her right eye. Cycloplegic refraction was-8.00-3.00×180º a...

The aim of this study was to determine the sensitivity of retinal areas involved in a localized retinal nerve fiber layer (RNFL) defect and to assess correlations between microperimetry and the standard full threshold central 30 deg visual field test. Twenty-five patients with focal RNFL defects, evaluated by means of Argon-blue scanning laser ophthalmoscopy (SLO), underwent an automated 30 deg...

BACKGROUND Headache is one of the most disturbing symptoms with common neurological signs. Variations in optic nerve perfusion quality or retinal microcirculation may end up in ganglion cell damage in patients with migraine. METHODS Sixty patients diagnosed with migraine and thirty normal individuals were evaluated in groups including migraine with aura, migraine without aura and controls. Re...

Recently developed optical techniques provide quantitative structural measurements of the retinal nerve fiber layer (RNFL). A complete interpretation of these measurements requires understanding of the optical properties of the RNFL. This paper gives a review of the polarization properties and relevant anatomy of the ocular tissues, followed by a thorough discussion of the optical properties of...