PURPOSE To examine characteristics of ocular hypertensive subjects and potential associations with estimated cerebrospinal fluid pressure (estCSFP). METHODS The population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6±9.8 years. Ocular hypertension was defined as intraocular pressure (IOP) >21 mmHg, normal optic nerve head appearance and normal retinal nerve f...

OBJECTIVE To quantitatively assess and compare the thickness of the retinal nerve fiber layer (RNFL) in ocular hypertensive eyes with normal and glaucomatous eyes using the Optical Coherence Tomograph (OCT 2000, software version A4X1; Humphrey Instruments, San Leandro, Calif). METHODS The mean RNFL thickness of ocular hypertensive (n = 28) eyes was compared with age-matched normal (n = 30) an...

Aim of work To evaluate the effect of refractive status and axial length of the eye on retinal nerve fiber layer (RNFL) thickness. Method A t tal of 116 eyes 62 subjects were enroll d in the study. RNFL thickness was measured using TOPCON 3D OCT 2000. Results Hyperopic group, as compared to normal, did not show any significant thickening for average, superior, inferior, nasal, and temporal quad...

INTRODUCTION Retinal structural changes in subjects with mild cognitive impairment (MCI) remain a subject of controversy. METHODS We investigated the correlation between optical coherence tomography (OCT) of the retinal sublayers, including the retinal nerve fiber layer (RNFL), and cognitive function in subjects with amnestic MCI and compared the OCT findings with matched controls. We also pe...

OBJECTIVE To study how customizing the peripapillary scan diameter on the basis of optic nerve head (ONH) diameter affects retinal nerve fiber layer (RNFL) thickness measurements using Stratus optical coherence tomography (OCT). METHODS Retinal nerve fiber layer was examined using 1 fixed-diameter circular scan (3.4 mm) and 2 customized-diameter scans (at 0.5 mm and 1 mm from the ONH edge) in...

Backgrounds: To evaluate changes in the thickness of ganglion cell-inner plexiform layer and macular retinal nerve fiber using ocular coherence tomography patients exposed to hydroxychloroquine .
 Methods: This was a retrospective, cross-sectional study on therapy. Ocular images showing cell were obtained compared controls. The relationship between layer, duration cumulative dose evaluated...

PURPOSE To demonstrate high-speed, ultrahigh-resolution, 3-dimensional optical coherence tomography (3D OCT) and new protocols for retinal imaging. METHODS Ultrahigh-resolution OCT using broadband light sources achieves axial image resolutions of approximately 2 microm compared with standard 10-microm-resolution OCT current commercial instruments. High-speed OCT using spectral/Fourier domain ...

To relate structural (anatomical) and functional (behavioral) measures of glaucomatous damage, a method is described for comparing visual field defects to local retinal ganglion cell (RGC) and retinal nerve fiber layer (RNFL) thicknesses. Thickness maps of the RNFL and the RGC + inner plexiform layer, obtained with frequency domain optical coherence tomography (fdOCT), were transformed into pro...

Introduction: For many years, amblyopia was regarded as a disorder of the visual system in which an organic cause could not be identified. Optical Coherence Tomography opens new horizons in understanding the etiopathology of amblyopia and seems to highlight morphologic anomalies in the retina of the amblyopic eye. Purpose: The objective of this paper is to analyze the macular thickness, optic n...

PURPOSE To specify thickness values of various retinal layers on macular spectral domain Optical Coherence Tomography (SDOCT) scans in patients with autosomal dominant optic atrophy (ADOA) compared to healthy controls. METHODS SDOCT volume scans of 7 patients with ADOA (OPA-1 mutation) and 14 healthy controls were quantitatively analyzed using manual grading software. Mean thickness values fo...