Osteoarthritis (OA) of the knee joint, most common form arthritis, is gradual degeneration joint cartilage. A progression OA characterized by degradation and articular cartilage with subchondral bone remodeling, osteophyte formation inflammation leading to bone-on-bone contact causing pain, stiffness, functional difficulties disability. affects patient’s quality life creates a significant finan...

conclusions our study demonstrates positive results (preservation or regeneration of bone) using prp in treatment of bronj. although prp may enhance osseous regeneration, long-term follow-ups are required to confirm its benefits. background bisphosphonate-related osteonecrosis of the jaws (bronj) is a well-known challenging entity warranting management. platelet-rich plasma (prp) plays an impor...

Tzong-Fu Kuo, Ming-Fang Lin, Yun-Ho Lin, Ying-Chun Lin, Rou-Jen Su, Hui-Wen Lin, Wing P. Chan I Graduate Institute of Veterinary Medicine, National Taiwan University, Taiwan, Republic of China. II Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taiwan, Republic of China. III Department of Pathology, School of Medicine, Taipei Medical University, Taiwan, Republic of China....

OBJECTIVE To evaluate the efficacy of platelet-rich plasma regarding healing, pain and hemostasis after total knee arthroplasty, by means of a blinded randomized controlled and blinded clinical study. METHODS Forty patients who were going to undergo implantation of a total knee prosthesis were selected and randomized. In 20 of these patients, platelet-rich plasma was applied before the joint ...

Platelet rich fibrin (PRF), developed in France by Choukroun et al(2001), is a second generation platelet concentrate widely used to accelerate soft and hard tissue healing. It’s advantages over the better known platelet rich plasma (PRP) include ease of preparation & application, minimal expense and no need of biochemical blood handling (no bovine thrombin or anticoagulants required). This art...

INTRO DUCTIO N Platelet-rich plasma is an autologous blood product that is being increasingly used to treat musculoskeletal conditions. Platelets have a rich store of factors and cytokines within their alpha granules and dense granules, which makes platelet-rich plasma an appealing therapeutic alternative. Some of the important factors found within the alpha granules of the platelet include pla...

Background: Cell therapy and cell culture have received much attention in recent decades. Suitable cell growth requires growth supplements such as fetal bovine serum (FBS). FBS is component rich in nutrients, growth factors and supplementary compounds. However, FBS utilization has some limitations including mass production. Therefore, finding alternatives with the same growth promoting effects ...