In this paper, a cardiac sense amplifier, i.e. the front end of a pacemaker, based on the Dynamic Translinear (DTL) circuit technique is presented. The system consists of a voltage-to-current converter, a bandpass filter, absolute value and RMS-DC converter circuits and an event detection circuit. From simulations, it is demonstrated that the DTL technique is a good alternative to conventional ...

Background: Whole-Body Vibration Training (WBVT) is a novel neuromuscular training method that has been recently developed as a rehabilitation tool. The purpose of this study was to determine whether WBVT is effective on electromyographic activity of the muscles of the lower limbs in patients with knee osteoarthritis.   Methods: The study was designed as a single blinded randomized clinic...

PURPOSE To determine the distribution of Zernike coefficients and higher order aberrations in a normal population and its relationship with age, gender, biometric components, and spherical equivalent. METHODS During the first phase of the Shahroud cohort study, 6311 people of the 40-64-year-old population of Shahroud city were selected through random cluster sampling. A subsample of participa...

Abstract  In this paper a new estimator for the measurement of the rms value of a noncoherent sampled sine-wave is proposed. The key feature of this estimator is that the sine-wave offset, a priori estimated, is removed from the sine-wave. A formula used to estimate the sinewave offset is also given in the paper. It has been proved by means of computer simulations and experimental results that...

This paper proposes a model of competitive bundling with an arbitrary number of …rms. In the regime of pure bundling, we …nd that relative to separate sales pure bundling tends to raise market prices, bene…t …rms, and harm consumers when the number of …rms is above a threshold. This is in contrast to the …ndings in the duopoly case on which the existing literature often focuses. Our analysis al...

BACKGROUND Precise measurement of the QT interval is often hampered by difficulty determining the end of the low amplitude T wave. Root mean square electrocardiography (RMS ECG) provides a novel alternative measure of ventricular repolarization. Experimental data have shown that the interval between the RMS ECG QRS and T wave peaks (RTPK) closely reflects the mean ventricular action potential d...

A new liaison role between Information Systems (IS) and users, the relationship manager (RM), has recently emerged. Accolding to the prescriptive literature, RMs add value by deep understanding of the businesses they serve and technologyleadership. Uttle is known, however, about their actual work practices. Is the RM an intermediary, filtering information and sometimes misinformation, from clie...

BACKGROUND Rhabdomyosarcoma (RMS) is a small round blue cell malignant tumor, representing 7% of childhood malignancies, and over 50% of all soft tissue sarcomas. Cyclophosphamide (CPA) is a prodrug and is the mainstay of RMS treatment. CYP2B6 is a highly polymorphic drug metabolizing enzyme involved in CPA bioactivation. The influence of CYP2B6 single nucleotide polymorphisms (SNPs) on the sur...