rosa damascena has been traditionally used as an herbal medicine for different therapeutic purposes. inorder to preliminarily study the probable toxic effects of the plant, its infusion was orally administered to 5groups of 5 dogs at doses 0.5-8 times that of human use in traditional medicine (90-1440 mg/kg/d) for 10successive days. the dogs in the control group (n=4) received placebo. serum le...

“VARD” formula consisting of Rosa damascena Mill. (Rosaceae) petal, and rhizomes of Glycyrrhiza glabra L. (Papilionaceae) and Nardostachys jatamansi DC. (Valerianaceae), has been proposed for gastric ulcer in Iranian traditional medicine. We investigated the antiulcer activity of each plant separately and in combination. The biochemical and molecular function of extracts was also evaluated. Eac...

Damask rose (Rosa damascena Mill.) has high economic importance and commercial value. The plant essential oil is used for perfumery, food and medicinal industries. It is necessary to know much about seed germination for study of genetic variation and breeding improved varieties of R. damascena. In this study seed germination of R. damascena were evaluated, using thermal period treatments. The d...

This research was done to test the effect of Rosa damascena essential oil on withdrawal signsof naloxone-precipitated morphine in male mice. Morphine dependence was induced by injection(IP) three times daily at doses of 50, 50 and 75 mg/kg, respectively, for 3 days. On day 4,after the last administration of morphine, Rosa damascena essential oil was administered atdifferent concentrations (5, 2...

Сучасним напрямком у конструюванні ефективних нетоксичних речовин є молекулярне моделювання на основі відомих природних та синтетичних сполук. Важливе місце як синтони для розробки займають азото-вмісні гетероцикли, зокрема хінолін. Серед похідних 3-((6-R-хінолін-4-іл)тіо) пропанової кислоти найбільш токсичними сполуки, які не мають в 6-му положенні хінолінового циклу алкоксизамісників 2-му пол...

Damask rose or Rosa damascena Herrm. is one of the most widely-used medicinal herbs in Iranian Traditional Medicine (ITM). Because of different types of phytochemicals such as flavonoids, glycosides, terpenes, and anthocyanins, R. damascena flowers have a wide range of pharmacological effects. Five traditional Rosa phytopharmaceuticals are “Golangebin”/ “Golq...