Royal jelly (RJ) has lots of compounds such as protein, vitamins, and a variety bioactive (10-hydroxy-2-decanoic or 10-HDA acids). is lipid fraction component in RJ content with antibacterial immunomodulatory activity. proteins that have antimicrobial, antifungal, anti-tumor, antidiabetic, antihypertensive properties. The authors continue their research about the effect on inhibitory strength g...

Background and aims: Highly active oxygen causes DNA or protein damage. This study aimed to determine the effect of extract three medicinal plants, royal jelly, metformin on survival human dermal fibroblast (HDF) cells under oxidative stress induced by H2 O2 . Methods: Hydroalcoholic extracts were prepared from Nigella sativa, Carum carvi seeds, Taraxacum officinale flower. The growth curve HDF...

The effective uptake of antigens (Ags) by specialized M cells of gut-associated lymphoid tissues is an important step in inducing an efficient intestinal mucosal immune response. In this study, royal jelly (RJ) was found to stimulate the differentiation of M-like cells from human Caco-2 cells in an in vitro M cell model. Furthermore, RJ and protease-treated royal jelly (pRJ) efficiently enhance...

This study aims to discover the characteristic chemical factors for determining region of royal jelly using machine learning. 84 samples from 13 different regions Turkey were used study, and parameters moisture, pH, acidity, 10-hydroxy-2-decanoic acid (10-HDA) investigated. ANOVA test was conducted determine whether there are differences between locations concerning four values. In addition sta...

We investigated the antifatigue effect of royal jelly (RJ), which had been stored at -20 degrees C from immediately after collection, in male Std ddY mice. The mice were accustomed to swimming in an adjustable-current swimming pool, then subjected to forced swimming five times during 2 wk, and the total swimming period until exhaustion was measured. They were separated into three groups with eq...

Symptoms of depression and anxiety appeared in mice after they had been subjected to a combination of forced swimming for 15 min followed by being kept in cages that were sequentially subjected to leaning, drenching, and rotation within 1-2 days for a total of 3 weeks. The animals were then evaluated by the tail-suspension test, elevated plus-maze test, and open-field test at 1 day after the en...