The role of breastfeeding in improving allergy outcomes in early childhood is still unclear. Evidence suggests that immune mediators in human milk (HM) play a critical role in infant immune maturation as well as protection against atopy/allergy development. We investigated relationships between levels of immune mediators in colostrum and mature milk and infant outcomes in the first year of life...

Diverse therapeutic strategies for food allergy are under investigation including food allergen-specific and nonspecific approaches. Allergen-specific approaches include immunotherapy with native food allergens, immunotherapy with mutated recombinant allergens, and diets containing extensively heated milk or egg. Native allergen immunotherapy can be administered via oral, sublingual, subcutaneo...

We examined the characteristics of food allergy prevalence and suggested the basis of dietary guidelines for patients with food allergies and atopic dermatitis. A total of 2,417 patients were enrolled in this study. Each subject underwent a skin prick test as well as serum immunoglobulin E (IgE) measurement. A double-blind, placebo-controlled food challenge was conducted using milk, eggs, wheat...

can cause morbidity in the infant or mother (or both), through inadequate intake of dietary components, especially calcium.6 In extreme cases this can lead to rickets.6 Acutely, IgE mediated cow’s milk allergy can result in anaphylaxis, hypoxia, and shock. Chronically, either form can lead to anaemia, hypoalbuminaemia, and faltering growth. Accurate diagnosis and engagement of families is there...

hydrolysate, soy and conventional cow milk formulas on incidence of atopic disease in high risk infants. Annals of Allergy 1989; 63: 102–6. 4 Chandra R. Five-year follow-up of high risk infants with family history of allergy who were exclusively breastfed or fed partial whey hydrolysate, soy and conventional cow’s milk formulas. Journal of Pediatriatric Gastroenterology and Nutrition 1997; 24: ...

OBJECTIVE To study the association between analfissures and cow's milk allergy (CMA) in infants. METHODS AND METHOD: In a prospective study, 72 confirmed cases of CMA in infants were examined for anal fissure by pediatricians with five years' experience. A positive finding was defined as when an anal fissure was detected by at least two out of three examiners. RESULTS Of infants with CMA with...

Background The prevalence of food allergy (FA) is increasing; consequently the number of patients on elimination diet (ED) due to a suspected diagnosis is also increasing. Diagnosis of food allergy should be based on a convincing history of allergic reactions or on the result of an oral food challenge test. The oral food challenge test (OFC) is the most reliable clinical procedure for diagnosin...

Oral immunotherapy (OIT) is used regularly for young children with cow's milk (CM) allergy and has been shown to be effective in several studies. However, adverse events occur frequently during OIT. Furthermore, there are only 5 randomized controlled trial studies of CM-OIT and these are low-powered single center trials. Therefore, evidence levels are also low and sometimes frequent and severe ...

hydrolysate, soy and conventional cow milk formulas on incidence of atopic disease in high risk infants. Annals of Allergy 1989; 63: 102–6. 4 Chandra R. Five-year follow-up of high risk infants with family history of allergy who were exclusively breastfed or fed partial whey hydrolysate, soy and conventional cow’s milk formulas. Journal of Pediatriatric Gastroenterology and Nutrition 1997; 24: ...

Cow's milk protein allergy is a growing problem in developed countries. We report the case of a Chinese infant, born at term, who presented on day 28 with severe growth failure, chronic diarrhoea, and metabolic acidosis. Investigations supported a diagnosis of cow's milk protein allergy. This was confirmed by withdrawing and reintroducing the relevant infant formula under controlled clinical co...