Planning and design procedure of an open pit mining project just can be started after ultimate pit determination. In the carried out study in this paper it was shown that the most important factor in ultimate pit determination and in consequence in the whole planning and design procedure of an open pit mine is the metal price. Metal price fluctuations in recent years were exaggerated and impose...

ABSTRACT Transverse sacral fracture is a very rare injury and frequently missed or delayed in diagnosis. We present a case with this injury and discuss its management. KEY WORDS Transverse, sacral fracture- dislocation, displacement.

Figure 1: Giant bilateral sacral Tarlov cysts (cysts have been marked along their span with arrows while the associated nerve roots have been encircled). Bukhari SS. Giant symptomatic bilateral sacral Tarlov cysts – a case report.

OBJECTIVE Radioimmunotherapy (RIT) has proven effective for patients with relapsed and refractory lymphoma. However, new types of therapy are strongly desired as B-cell lymphoma remains incurable for many patients. Photoimmunotherapy (PIT) is an emerging targeted cancer therapy that uses photosensitizer (IR700)-conjugated monoclonal antibodies (mAbs) to specifically kill cancer cells. To evalua...

PURPOSE We evaluated the results of treatment of neurogenic bladder dysfunction in spinal cord injury by sacral posterior root rhizotomy and anterior sacral root stimulation using the Finetech-Brindley stimulator. MATERIALS AND METHODS In 52 patients with spinal cord lesions and urological problems due to hyperreflexia of the bladder complete posterior sacral root rhizotomy was performed and ...

[Purpose] The purpose of this study was to investigate the influence of sacral sitting in a wheelchair on contact pressure on the buttocks and back, and shear force on the ischial region. [Subjects and Methods] Twenty-six healthy adults assumed two postures while seated in a wheelchair: a basic sitting posture, and sacral sitting with the pelvis tilted posteriorly and the ischium slid forward b...

Pituitary protein transcription factor (Pit-1) is a member of a large family of protein transcription factors that include Pit-1, Oct-1, Oct-2, and Unc-86. The goal of this experiment was to determine whether the population of Pit-1-containing cells changes in the anterior pituitary of chicken by the regulation of feeding. White Leghorn hens were subjected to withdrawal and resumption of feedin...

The transcription factor Pit-1/GHF-1 plays an important role in regulating the prolactin (Prl) and growth hormone (GH) genes in mammals. In this study, the role that Pit-1 plays in regulating the prolactin and growth hormone genes in avian species was examined by cotransfection assays and immunofluorescence staining of pituitary sections. In cotransfection assays, turkey Pit-1 activated the tur...

Activation of the human growth hormone (hGH-N) gene in pituitary somatotropes is mediated by a locus control region (LCR). This LCR is composed of DNase I-hypersensitive sites (HS) located -14.5 kb to -32 kb relative to the hGH-N promoter. HSI, at -14.5 kb, is the dominant determinant of hGH-N expression and is essential for establishment of a 32-kb domain of histone acetylation that encompasse...

CONTEXT Mosaic trisomy 9 is considered to be a rare chromosomal abnormality with limited survival. Our objective was to report on two patients with mosaic trisomy 9 presenting unusual findings and prolonged survival. CASE REPORTS The first patient was a boy aged six years and five months presenting weight of 14.5 kg (< P3), height of 112 cm (P10), head circumference of 49 cm (P2), prominent f...