PurposeLeft ventricular assist devices (LVAD) are standard of care for management end-stage heart failure. LVAD patients on antiplatelet agents and long-term anticoagulation with warfarin to prevent thrombotic events. The ease use, superior efficacy, improved side effect profile have made direct oral anticoagulants (DOACs) the preferable anticoagulant treatment atrial fibrillation; but there is...

Failure is one key problem of MEMS S&A (safety and arming) device for its practical application. To make research of failure of MEMS S&A device in action process, a method based on FTA was employed to make analysis on arming process of the set-back arming mechanism of typical MEMS S&A device. Result obtained with theory computation was verified to be right by simulation analysis and which could...

background and objective: there is a concern on safety of human fresh frozen plasma (ffp) as it is a source of some medicinal products. the possibility of transmission of blood-borne are reported often due to emerging viruses. there are some pathogen reduction technologies (prt) to inactivate viruses. methylene blue (mb) based method is one of them. the aim of this study was to examine new desi...

The on-demand approach, where systems are assembled from components by lay users, has seen success in the consumer electronics industry. Currently, there is growing demand for on-demand capabilities in medical systems so caregivers can create larger medical systems from smaller medical devices. Unlike consumer electronics, medical systems pose challenges for the on-demand approach due to attrib...

To cite: Padmanabhan C, Jagannathan R, Talluri K, et al. BMJ Innov Published Online First: [please include Day Month Year] doi:10.1136/bmjinnov-2016000115 ABSTRACT Background Heart failure is frequently associated with severely impaired ventricular function and manifests often with functional mitral regurgitation (FMR). This is a complex syndrome that is primarily due to abnormal function of th...