Spatial interpolation methods are widely used in various fields and have been studied by several scholars with one or a few specific sampling datasets that do not reflect the complexity of the spatial characteristics and lead to conclusions that cannot be widely applied. In this paper, three factors that affect the accuracy of interpolation have been considered, i.e., sampling density, sampling...

Once the research question and the research design have been finalised, it is important to select the appropriate sample for the study. The method by which the researcher selects the sample is the ' Sampling Method'. There are essentially two types of sampling methods: 1) probability sampling - based on chance events (such as random numbers, flipping a coin etc.); and 2) non-probability samplin...

Umbrella sampling is an efficient method for the calculation of free energy changes of a system along well-defined reaction coordinates. However, when there exist multiple parallel channels along the reaction coordinate or hidden barriers in directions perpendicular to the reaction coordinate, it is difficult for conventional umbrella sampling to reach convergent sampling within limited simulat...