To explore the cellular adaptations and responses to hypoxia in normal human saphenous vein smooth muscle cells (SMCs) and presume what roles phenotypic modulation of normal human saphenous vein SMCs would play in varicose vein of lower extremity, we used cobalt chloride (CoCl2), a hypoxia mimetic, to treat normal human saphenous vein SMCs in vitro. The proliferating ability of cells exposed to...

BACKGROUND Saphenous vein graft thrombosis can present as unstable angina. However, percutaneous coronary intervention for saphenous vein graft lesions poses a high risk of slow flow related to the procedure. Here we present the utilization of the novel oral anticoagulant, apixaban, in the treatment of unstable angina with extensive saphenous vein graft thrombus, leading to considerable thrombu...

S. Large saphenous vein graft aneurysm with a fistula to the right atrium. Superior vena cava syndrome secondary to saphenous venous graft aneurysm with right atrial fistula. Giant true saphenous vein graft aneurysm causing cardiac compression: a rare cause of atrial flutter. A large coronary artery saphenous vein bypass graft aneurysm with a fistula: case report and review of the literature.ti...

The saphenous venous system was visualized by CT without any contrast medium injection. Volumetric data were acquired with a multidetector spiral CT (Siemens, Somatom Plus 4 Volume Zoom) with the following parameters: collimation, 1 mm; pitch, 4; reconstruction, 1.2 mm. Reformatted images were then transferred in DICOM format to an 02 work station (Silicon Graphics) and postprocessed by the sof...

OBJECTIVE The saphenous vein is the most commonly used graft in coronary artery bypass surgery, since no suitable arterial graft is available. However, the frequency of late graft failure is a cause for research into graft protection. The objective of this study was to investigate the effect of synthetic adhesive cyanoacrylate administration on the saphenous vein graft for preventing vascular d...

The Falck fluorescence histochemical method was used to compare the adrenergic innervation in segments from the proximal saphenous artery, the distal saphenous artery and the popliteal artery. Adrenergic neurons penetrated the media of the proximal saphenous artery but not that of the distal saphenous artery or the popliteal artery. Responses of these vessel segments to exogenous Z-norepinephri...

BACKGROUND The endocannabinoid system has been shown to reduce inflammatory flares and pain in rodent models of arthritis. A limitation of endocannabinoids is that they are rapidly denatured by hydrolysing enzymes such as fatty acid amide hydrolase (FAAH) which renders them physiologically inert. Osteoarthritis (OA) is primarily a degenerative joint disease; however, it can incorporate mild inf...

OBJECTIVES: This study compared radiofrequency ablation versus conventional surgery in patients who had not undergone previous treatment for bilateral great saphenous vein insufficiency, with each patient serving as his own control. METHOD: This was a randomized controlled trial that included 18 patients and was carried out between November 2013 and May 2015. Each of the lower limbs of each p...

PURPOSE Sciatic nerve block in the popliteal fossa (popliteal nerve block, PNB) is an anaesthetic technique well-suited for operations below the knee. However, difficulty with positioning the patient in the prone position often precludes the classical, posterior approach to the block. In this report, an alternative approach to PNB that can easily be performed with a patient in the supine positi...

BACKGROUND Bucket-handle meniscus tears (BHMT) are often displaced and unstable. The inside-out technique of repairing such tears is currently the gold standard. All-inside repair with meniscal fixators is getting increasingly popular. Shortcomings of the inside-out technique include neurovascular complications, especially saphenous nerve palsy, and retention of a non-resorbable suture which ca...