We describe a case of young adult female with Henoch-Schonlein purpura (HSP) presenting cutaneous and gastrointestinal manifestations. Biopsy revealed leukocytoclastic vasculitis in the skin. Steroid therapy led to initial resolution symptoms followed by relapse rashes subsequent introduction azathioprine. HSP is most common childhood uncommonly seen adults. Early recognition disease, especiall...

Henoch-Schonlein purpura (HSP) is a self-limited autoimmune disease, the cause of which is not clear. Gastrointestinal involvement is often the main symptom of HSP. We report an unusual and rare case in a patient who was diagnosed with HSP. This is the second report of terminal ileitis induced by HSP that presented as acute appendicitis. We report a 21-year-old man who presented with right lowe...

INTRODUCTION Henoch-Schönlein purpura is a common immunoglobulin A-mediated vasculitic syndrome in children, characterized by purpuric rash, arthritis and abdominal pain. Renal involvement, manifested by the presence of hematuria and/or proteinuria, is also frequently seen. In most cases, patients with this disease achieve complete recovery, but some progress to renal impairment. Gastro-intesti...

Diagnosing HSP can be difficult, especially when abdominal symptoms precede the onset of characteristic palpable purpura (Chen MJ et al. 2005, World Gastroenterol., 11, 2354). Therefore, it is necessary to consider the possibility of HSP in patients with prolonged strong abdominal pain, even in cases without purpura.

We read with interest the article " Henoch-Schönlein Purpura in adults " by López Meiller et al. 1 They reported 3 adult patients with Henoch-Schönlein nephritis (HSN) (one with hematuria and two with heavy proteinuria) who were treated with IV cyclophosphamide (1g/m²/month for six months). 1 Although the treatments of severe Henoch-Schönlein nephritis still remains controversial, oral cyclopho...

BACKGROUND Henoch-Schönlein Purpura (HSP) is an IgA small-vessel vasculitis that is primarily a disease of childhood. Its presentation in adulthood is rare and has a more severe disease course. We present a case with an atypical presentation of this disease that was a diagnostic challenge for multiple providers. CASE REPORT A 42-year-old man noticed bullous lesions over his ankles that spread...

Henoch-Schonlein Purpura (HSP) is the commonest vasculitis in children, and outcome depends on renal involvement or occurrence of HSP nephritis (HSPN). Hence, a meticulous diagnosis, treatment regular follow-up plan needed for better prognosis. A case 12 - year old girl showing HSPN symptoms only eight weeks after first onset reported. Symptoms might appear later, hence emphasising importance c...

Henoch-Schönlein purpura commonly occurs in children at about age five. There is no known etiologic agent. The illness is characterized by skin rash, joint pain, edema and gastrointestinal symptoms. Laboratory tests are not diagnostic. Although there is no specific treatment, steroids may help prevent serious gastrointestinal complications. Prognosis is good, except for those patients with adva...

We reported the gastrointestinal (GI) endoscopic findings in a 12-year-old boy with Henoch-Schönlein purpura (HSP). The patient presented with massive rectal bleeding and abdominal pain, requiring multiple blood transfusions. The colonoscopic examination revealed colonic lymphonodular hyperplasia with mild mucosal erythema. The biopsies showed erosive colitis with vascular fibrinoid necrosis. C...