The Departments of Preventive Medicine and Public Health in Kansas City and Wichita are passionate about healthy communities and are committed to improving the health of people through teaching, research and service. Our faculty, which includes physicians, epidemiologists, social scientists, and research scientists, conduct research and work in the community to harness public health and scienti...

NAD(+) is a central metabolite in the cell. Changes in NAD(+) abundance and the activity of NAD(+)-dependent enzymes, such as the sirtuins, are at the core of metabolic/mitochondrial diseases, such as obesity and diabetes, and of cancer and neurodegeneration. Here, we discuss how maintaining or raising NAD(+) levels can improve metabolism and prevent age-related functional decline and associate...

deep brain stimulation (dbs) is a neurosurgical procedure that enables brain structures to be stimulated electrically by a pacemaker implanted under the skin. in the 1980s, over a decade after its first use in pain, implantable dbs of the thalamus was performed to suppress tremor in parkinson’s disease (pd) refractory to drug treatments. primate-based research soon afterwards identified the sub...

As one of the first to work at the Carnegie Institution of Washington [5] Department of Embryology, Warren Harmon Lewis made a number of contributions to the field of embryology [6]. In addition to his experimental discoveries on muscle development and the eye, Lewis also published and revised numerous works of scientific literature, including papers in the Carnegie Contributions to Embryology ...

The Molecular Parasitology conference was first held at the Marine Biological laboratory, Woods Hole, USA 25 years ago. Since that first meeting, the conference has evolved and expanded but has remained the showcase for the latest research developments in molecular parasitology. In this perspective, I reflect on the scientific discoveries focussed on African trypanosomes (Trypanosoma brucei spp...

It is probably unprecedented that an afterdinner speech for the general public is converted into a review article that, 65 years later, is still on an exponential growth curve of citations in the primary scientific literature. But then again, Archibald Vivian Hill was not your average after-dinner speaker. Hill shared a Nobel Prize in 1922 for his discoveries related to muscle heat production a...