Scrub typhus is an important emerging tropical infection that can have severe manifestations in children leading to intensive care admission. It is caused by Orientia tsutsugamushi, a gram negative bacterium transmitted to humans by the bite of larval trombiculid mites. The organism is endemic in south-east Asia and the disease is reported from virtually all parts of India. The hallmark of this...

Guillain – Barre syndrome with no known etiology: Rule out scrub typhus - IJCA- Print ISSN No: 2394-4781 Online No:- 2394-4994 Article DOI 10.18231/j.ijca.2023.046, Indian Journal of Clinical Anaesthesia-Indian J Clin Anaesth

We conducted serodiagnostic testing for dengue virus infection, murine typhus, scrub typhus and leptospirosis in Plasmodium falciparum-infected individuals in Thailand. Sera from 194 malaria patients with a median age of 24 years were tested. No antibody titers diagnostic of dengue virus infection were demonstrated, but 29 (15%) of patients had serological evidence of scrub typhus, 45 (23.2 %) ...

Rickettsial diseases have affected the military throughout history. Efforts such as those of the Joint U.S. Typhus Commission near the beginning of World War II and of military researchers since have reduced the impact of these diseases on U.S. and Allied forces. Despite the postwar development of effective antibiotic therapies, the newly emerging antibiotic-resistant scrub typhus rickettsial s...

Scrub typhus has a wide range of clinical presentation varying from mild symptoms like fever, chills, headaches, myalgias, gastric ulcerations and hepatitis to more fatal conditions pneumonia encephalopathy caused by disseminated vasculitis with splenic infarct being rare complication. We report case 50-years old male scrub who presented as multiple infarcts.

Since the outbreak of the recent war a number of contributions have been made to the chemotherapy of rickettsial diseases. Forbisen (4-41-bis-antipyrine) and toluidine blue (TB) were shown to be active against routine typhus infections in mice (1). Although found to be effective against pulmonary infections in mice with murine and epidemic rickettsiae, p-sulfamidobenzamidine and p-sulfamidobenz...

Background: Scrub typhus, also known as tsutsugamushi disease, is an infectious illness caused by Orientia (Rickettsia) tsutsugamushi. It is widely found in Asian counztries and human beings of all ages including children are influenced by it. It can cause death due to late presentation, delayed diagnosis and drug resistance. The clinical features and complications of scrub typhus vary from mil...

E1152 CMAJ, October 18, 2011, 183(15) © 2011 Canadian Medical Association or its licensors A33-year-old man from a rural Taiwanese village was admitted with a three-day history of fever, headache, muscle pain and skin rashes. On examination, he was febrile (39.2°C) with generalized macular patches and an eschar measuring 15 mm on the left lower quadrant of his abdomen (Figure 1). His leukocyte ...

A 67-year-old woman presented with melena and general weakness. Upper gastrointestinal (GI) endoscopy revealed multiple ulcers and projectile bleeding in the stomach. She also complained of a 10-day history of a fever and was diagnosed with scrub typhus based on a positive result of the eschar polymerase chain reaction (PCR) testing. She fully recovered with endoscopic hemostasis, and administr...

BACKGROUND Scrub typhus, a zoonosis caused by Orientia tsutsugamushi, is a systemic febrile illness. The disease presents with diverse clinical manifestations, ranging from subclinical disease to multiorgan failure and fatal disease. It may rarely present as an acute abdomen which may lead to a diagnostic dilemma. We describe two serologically confirmed cases of scrub typhus presenting as acute...