It is generally believed that prokaryotic translation is initiated by the interaction between the Shine-Dalgarno (SD) sequence in the 5' UTR of an mRNA and the anti-SD sequence in the 3' end of a 16S ribosomal RNA. However, there are two exceptional mechanisms, which do not require the SD sequence for translation initiation: one is mediated by a ribosomal protein S1 (RPS1) and the other used le...

INTRODUCTION Hyperprolactinemia is a common side-effect of antipsychotic treatment. Antipsychotics and hyperprolactinemia are both considered risk factors of metabolic disturbances and diabetes. Investigations on prolactin response to meal ingestion in antipsychotic-treated patients are missing. MATERIAL AND METHODS In a case-control design, 49 antipsychotic-treated, clinically stable, non-di...

OBJECTIVE To determine the anthropometric profile of urban adult black Malawians. DESIGN A cross sectional study of adult subjects. SETTING The subjects were recruited from two townships of Kachere and Bangwe, Blantyre. SUBJECTS Eight hundred and ninety eight urban adults, 583 males and 315 females aged sixteen to sixty years. were randomly selected. Only those who could identify both par...

BACKGROUND Central obesity is associated with peripheral arterial disease, suggesting that ectopic fat depots may be associated with localized diseases of the aorta and lower-extremity arteries. We hypothesized that persons with greater amounts of periaortic fat are more likely to have clinical PAD and a low ankle-brachial index. METHODS AND RESULTS We quantified periaortic fat surrounding th...

Some diseases may underlie finger clubbing. However, there is a dearth of information about early stage of finger clubbing because only few researchers have shown interest in it. We determined the Digital Index of normal, healthy subjects by using thread and manual Vernier calipers, the time used for the procedure, and its interrater reliability. The value of Digital Index was 8.86 ± 0.29 (Mean...

OBJECTIVE To examine whether circulating leptin levels correlate with the severity of disease in patients with obstructive sleep apnea. DESIGN Prospective nonrandomized study. SETTING Referral sleep laboratory for patients with sleep-disordered breathing and biochemistry laboratory. Patients Thirty-two subjects (mean +/- SD age, 47 +/- 12 years) who were referred for suspected sleep apnea u...

The relationship between the Electrophoretic Mobility of Cell Nuclei (EMN) index before and after super-maximal and maximal exercises and changes in physiological parameters associated with acid-base balance of the blood (pH, BE) and lactic acid concentration (LA) were examined in junior (N = 33, X = 15.6 y.o. SD = 1.16 y.), and senior (N = 10, X = 22.0 y.o. SD = 2.70 y.) female rowers. The fol...

Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan validitas reliabilitas tes hasil belajar IPS dengan kuesioner motivasi siswa kelas IV SD. merupakan jenis penelitian pengembangan atau Research and Development (R&D) melalui empat tahapan yaitu pendefinisian, perencanaan, penyebarluasan. Subyek adalah guru SD dosen. Data yang dikumpulkan IPS, SD, Validitas dianalisis menggunakan ...