Vitiligo is a depigmentation disorder that commonly found in the community. The causes of vitiligo are multifactorial such as genetic and environmental factors accompanied by presence non-specific specific immune system factors. Melanocytes main target exposed reactive oxygen species (ROS) during process melanogenesis. Such exposure can cause loss homeostasis cell death has implications for vit...

We present two cases of segmental arterial mediolysis, which can present with dissecting aneurysms or thrombosis of the visceral branches of the abdominal aorta. Segmental arterial mediolysis (SAM) causes ischemic bowel disease and has characteristic CT and angiographic features.

Limited comparative studies suggest that the human genome is particularly enriched for recent segmental duplications. The extent of segmental duplications in other mammalian genomes is unknown and confounded by methodological differences in genome assembly. Here, we present a detailed analysis of recent duplication content within the mouse genome using a whole-genome assembly comparison method ...

STUDY DESIGN Segmental arteries were interrupted bilaterally at up to three levels to study the influence on spinal cord blood flow (SCBF) and function in dogs. OBJECTIVES Considering the need to limit blood loss during surgery for spinal tumors, such as total en bloc spondylectomy, we studied the SCBF and function after experimental interruption of segmental arteries at up to three levels. ...

i.e. X can be written as a sum of three outer products of the respective component vectors, which constitute rank-1 matrices. Let A := [a1, a2, a3] and B := [b1, b2, b3], and X can be expressed as X = AB. Note the trivial fact that ATTB = X for any invertible T; hence, given X, infinitely many (A, B) pairs can potentially give rise to X. Unless some additional structure is assumed or JOURNAL OF...

We consider a key case in the fundamental and substantial problem of the possible Jordan canonical forms of A, B,C ∈Mn(F ) when C = AB. If A ∈ M2k(F ) (respectively B, C ∈ M2k(F ) ) is diagonalizable with two distinct eigenvalues a1, a2 (respectively b1, b2, and c1, c2), each with multiplicity k, and when C = AB, all possibilities for a1, a2, b1, b2, c1, c2 are characterized. The possibilities ...

The development of immune checkpoint inhibitors such as programmed cell-death receptor 1 (PD-1) antagonists has rapidly advanced chemotherapy within the last several decades. PD-1 targeted immunotherapy drugs like pembrolizumab, ipilimumab, nivolumab, and durvalumab have known associations with immune-mediated dermatological reactions. We report a case in which an elderly male experienced segme...

conclusion the possibility of malignancy is strongly indicated when additional nme lesions show linear or segmental enhancement on preoperative 3t dce-mri in patients with recently diagnosed breast cancer. results on histopathologic analysis of the 88 nme lesions, 73 (83%) were malignant and 15 (17%) were benign. lesion size did not differ significantly between malignant and benign lesions (p =...