Abstract Background Allergic rhinitis is the most prevalent allergic disease, and prevalence sensitization patterns differ among countries. Identifying common inhalant allergen in each region plays a key role diagnosis management of rhinitis. There are no data available about aeroallergen patients Egypt. The aim this study to evaluate positive serum allergen-specific IGE allergens A cross-secti...

Sensitization refers to an increase in sensitivity to the effects of a drug and is believed to play a role in the etiology of substance use disorders. Cross-sensitization has been observed between drugs from different pharmacological classes and may play a role in the escalation of drug use in polydrug-abusing populations. The purpose of this study was to examine cross-sensitization between opi...

Flying insects have developed a remarkably sensitive olfactory system to detect faint and turbulent odor traces. This ability is linked to the olfactory receptors class of odorant receptors (ORs), occurring exclusively in winged insects. ORs form heteromeric complexes of an odorant specific receptor protein (OrX) and a highly conserved co-receptor protein (Orco). The ORs form ligand gated ion c...

Lung cancer is managed using conventional therapies, including chemotherapy, radiation therapy, or a combination of both. Each these therapies has its own limitations, such as the indiscriminate killing normal well cells, solubility chemotherapeutic drugs, rapid clearance drugs from circulation before reaching tumor site, resistance cells to radiation, and over-sensitization radiation. Other tr...

Primary allergic sensitization--IgE formation after Ag exposure--is fundamental in the development of allergic respiratory disease. With the rising prevalence of asthma and allergic rhinitis, improved understanding of the determining factors for allergic sensitization is needed. Human epidemiologic studies suggest high-dose allergen exposure may paradoxically protect against sensitization. Pros...

introduction: tooth pain and sensitization are the two main causes of discomfort after periodontal flap surgery. effects of low level laser therapy for reducing pain have already been established; these kinds of lasers have been used for tooth desensitization as well. this controlled blind study sought to compare tooth pain and sensitization after 660nm laser irradiation in a split mouth and al...

The paper discusses spectral sensitized photo processes in silver bromide caused by dyes adsorbed on the surface of stearate via lightguide mechanism and a direct hit luminescent light from dye molecules localized near microcrystal to bromide. submits an estimation contribution overall sensitization. These calculations demonstrate that particle sensitization stearate—silver structure is compara...

Prostaglandin E(2) (PGE(2)) is a key mediator of exaggerated pain sensation during inflammation. Drugs targeting the PGE(2) pathway by global inhibition of cyclooxygenases are well established in the treatment of inflammatory pain, but also cause significant unwanted effects. Enzymes downstream of the cyclooxygenases, or prostaglandin receptors are candidate targets possibly enabling therapeuti...

erythropoietin (epo) was first known as a factor for red blood cell proliferation and differentiation. recent studies show the effects of epo on immune system. in this study the antihuman leukocyte antibody (anti-hla) titer were determined in five groups of rats, which had been sensitized with human lymphocyte. also, the effects of stimulation's frequency and dose of recombinant human eryt...

This target article examines the clinical and experimental evidence for a role of peripheral and central hyperexcitability in persistent pain in four key areas: cutaneous hyperalgesia, referred pain, neuropathic pain, and postoperative pain. Each suggests that persistent pain depends not only on central sensitization, but also on inputs from damaged peripheral tissue. It is instructive to think...