1 Associate Professor, 2* Assistant Professor, 3 Post Graduate, 4 Professor: Department of Anesthesiology, Gandhi Medical College, Padmarao Nagar, Secunderabad, Telangana *Corresponding Author Dr .D. Suresh Chander Associate Professor, Dept of Anesthesiology, Gandhi Medical College, Padmarao Nagar, Secunderabad, Email: [email protected] ABSTRACT Background: The present study was desig...

Aims and Objectives: Spinal anaesthesia is the most commonly used method of anaesthesia and analgesia in lower limb surgeries. In elderly patients spinal anaesthesia causes more sympatholysis and hemodynamic disturbances than young patients. So low dose of local anaesthetic is preferred which may occasionally cause failure of spinal anaesthesia .Therefore, different adjuvents are added to achie...

The parabrachial nucleus (PBN) has been proposed as the associative site for conditioned taste aversion. Previous evidence has shown that functional blockade of the PBN by tetrodotoxin (TTX) produces retrograde disruption of lithium-induced taste aversions in rats. However, given the PBN role in processing visceral cues and the long duration of the lithium-induced aversive effects, an interpret...

BACKGROUND The administration of oral pregabalin preoperatively has been reported to reduce acute postoperative pain. However, no clinical study to date has yet fully investigated whether or not pregabalin premedication affects sensory and motor blocks using spinal anesthesia and its effect upon early postoperative pain management. This prospective, randomized, and double-blind clinical study w...

INTRODUCTION Celecoxib in a dose of 200 mg is safe for the breast feeding mother, as its milk levels are extremely low. We investigated the efficacy of celecoxib in improving postoperative pain management in parturients under patient-controlled epidural analgesia (PCEA). MATERIAL AND METHODS We studied 64 healthy parturients undergoing elective caesarean section under combined spinal-epidural...

OBJECTIVE Epidural (EA) and combined spinal-epidural (CSE) techniques have both been utilized for labor analgesia. This study compared the effects on the mother and newborn of these techniques in labor analgesia and anesthesia. METHODS Forty pregnant women received epidural analgesia with 15 mL of 0.125% ropivacaine (EA group) and 5 microg of sufentanil plus 2.5mg bupivacaine in the subarachn...

The ultimate aim of the initiating the study was find out effect of admixture of Clonidine and/or Epinephrine on Lignocaine. After coadministering clonidine (150 μg, n=20) or Epinephrine (200 μg, n=20) to Lignocaine, end points like sensory or motor blockade, depth of anesthesia, cool and hot sensation, plasma level of Lignocaine was studied. Total 60 subjects received the combination aforesaid...

BACKGROUND Circadian variations in the absorption, distribution, protein binding, elimination and metabolism of drugs account for many of the administration-time-dependent differences in their pharmacokinetics. The aim of this study is to determine whether the time of intrathecal injection influences spinal anesthesia. METHODS Ninety patients scheduled for orthopedic surgery were randomly ass...

BACKGROUND The supplementation of local anaesthetics with adjuvants to improve the efficacy of subarachnoid block has been recognised since long. The most preferred drug has been opioids, but newer drugs like dexmedetomidine has also been introduced and investigated as an effective adjuvant. AIM This study was conducted to evaluate and compare the characteristics of subarachnoid blockade, hem...

BACKGROUND AND AIMS The supraclavicular and infraclavicular brachial plexus blocks have a similar distribution of anaesthesia, and both can be used effectively for surgeries of the upper limb. This study aimed to compare the supraclavicular and infraclavicular approaches of brachial plexus blocks, guided by ultrasound and neurostimulation. METHODS Sixty adult patients scheduled for elective u...