BACKGROUND Both genetic and environmental factors play a role in the pathogenesis of type 2 diabetes and cardiovascular diseases. The magnitude of genetic and environmental influences may vary in different populations and can be investigated by twin studies. METHODS In this cross-sectional study, 101 (63 monozygotic and 38 dizygotic) adult twin pairs (n = 202; mean age: 44.3 ± 15.8 years) wer...

Serum factors reactive with human heart or extracts of human heart have been found by a number of investigators utilizing a variety of immunologic techniques (1-7). Kaplan, Meyeserian, and Kushner (8) have demonstrated reactive factors in the sera of patients with acute rheumatic fever and certain other diseases by an immunofluorescent technique. The present study, using the immunofluorescent m...

he was taking a minimum of 256 units daily. Thereafter the dosage dropped progressively, but seven weeks later he still needed up to 188 units daily. He was then transferred to Actrapid MC. In three days his insulin requirement fell by 36 % to 102 units daily. He was stabilised on twice daily Actrapid MC in a total dose of 112-124 units daily and remained well controlled, with a mean mid-mornin...

Background: Assessment of AMH cut-off levels in serum and in follicle fluid (FF) for patients with (group 2, n=34) and without (group1, n= 96) endocrinological risk factors, such as ovarian hyperstimulation syndrome (OHSS) and polycystic ovary syndrome (PCOS), is clinically useful in optimising the treatment protocol. Materials and Methods: AMH was analysed in serum and FF of 130 infertile pati...

introduction regular intake of n-3 fatty acids of marine origin have desirable effects on serum lipoproteins and reduce coronary vascular disease (cvd). n-3 fatty acid supplementation decreased serum triglyceride concentrations in studies in which most of the subjects were male. the effects of n-3 fatty acids supplementation in fat women especially postmenopausal fat women have received little ...

As revealed by appropriate fractionation procedures, human serum deficient in alpha(1)-antitrypsin (alpha(1)-AT) is also deficient in the naturally occurring chemotactic factor inactivator. These serum donors had severe pulmonary emphysema. Serum from patients with clinically similar pulmonary disease, but with presence of alpha(1)-AT in the serum, showed no such deficiency of the chemotactic f...

Collapsin response mediator proteins (CRMPs) are intracellular proteins that mediate signals for several extracellular molecules, such as Semaphorin3A and neurotrophins. The phosphorylation of CRMP1 and CRMP2 by Cdk5 at Ser522 is involved in axonal guidance and spine development. Here, we found that the Ser522-phosphorylated CRMP1 and/or CRMP2 are enriched in the dendrites of cultured cortical ...

When Miss Ethel Douglas Hume brought out Bechamp or Pasteur? in 1923, it appeared to be just the thing that would fill this gap and end the use of serums and other biologicals forever. But it is now 19 years since that book, which should have marked an epoch in the healing arts, appeared. It did not receive the attention it deserved in medical circles and, though it is now in its second edition...

Background: Autologous serum skin test (ASST) evaluates the presence of any serum histamine-releasing factors and histamine-releasing autoantibodies. Autologous serum therapy (AST) is a therapy in which repeated injections of autologous serum are administered intramuscularly for treatment of chronicspontaneous urticaria (CSU). The aim of this study is to evaluate the advantages and compare the ...