نتایج جستجو برای: severe refractory angina

تعداد نتایج: 396759  

Journal: :American journal of cardiovascular drugs : drugs, devices, and other interventions 2001
S M Killalea H Krum

Perhexiline was introduced about 30 years ago and rapidly gained a reputation for efficacy in the management of angina pectoris. However, hepatic and neurological adverse effects associated with perhexiline administration led to a marked decline in its use. The drug was originally classified as a coronary vasodilator, and later as a calcium channel antagonist, but recent data suggests that it a...

Journal: :Heart 1999
S Murray K G Carson P D Ewings P D Collins M A James

OBJECTIVE To assess the impact of spinal cord stimulation (SCS) on the need for acute admissions for chest pain in patients with refractory angina pectoris. DESIGN Retrospective analysis of case records. PATIENTS 19 consecutive patients implanted for SCS between 1987 and 1997. All had three vessel coronary disease, and all were in New York Heart Association functional group III/IV. METHOD...

Journal: :The New England journal of medicine 2015
Stefan Verheye E Marc Jolicœur Miles W Behan Thomas Pettersson Paul Sainsbury Jonathan Hill Mathias Vrolix Pierfrancesco Agostoni Thomas Engstrom Marino Labinaz Ranil de Silva Marc Schwartz Nathalie Meyten Neal G Uren Serge Doucet Jean-François Tanguay Steven Lindsay Timothy D Henry Christopher J White Elazer R Edelman Shmuel Banai

BACKGROUND Many patients with coronary artery disease who are not candidates for revascularization have refractory angina despite standard medical therapy. The balloon-expandable, stainless steel, hourglass-shaped, coronary-sinus reducing device creates a focal narrowing and increases pressure in the coronary sinus, thus redistributing blood into ischemic myocardium. METHODS We randomly assig...

Journal: :European respiratory review : an official journal of the European Respiratory Society 2013
Reinier R L Wener Elisabeth H Bel

Asthma is a heterogeneous disease in which adequate asthma control cannot be achieved in a substantial proportion despite currently available treatment possibilities. This subgroup has been defined as "severe refractory" asthma. Over the past years considerable progress has been made regarding a more exact definition of severe refractory asthma. A systematic approach to evaluate the asthma pati...

Journal: :British medical journal 1969
P B Fowler H Ikram R N Maini A R Makey J S Kirkham

A patient with a sinus bradycardia and angina is described who was unable to increase his heart rate on vigorous exercise by more than a few beats. His severe angina was attributed to the bradycardia. Atrial pacing of his heart abolished his angina and increased his exercise tolerance. Circulatory changes at rest, on exertion, and with atrial pacing are described. The cause of angina in this pa...

Journal: :Palliative medicine 2010
Hannah Osborn Melanie Jefferson

Chronic refractory angina can lead to multiple acute hospital admissions. This can be due to patient and healthcare professional misconceptions regarding the meaning of the chest pain experienced. Symptom control, psychological support and education form an important part of the management of this condition. We describe a case study where intranasal alfentanil provided rapid relief of symptoms ...

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