INTRODUCTION Biphasic positive airway pressure (BIVENT) is a partial support mode that employs pressure-controlled, time-cycled ventilation set at two levels of continuous positive airway pressure with unrestricted spontaneous breathing. BIVENT can modulate inspiratory effort by modifying the frequency of controlled breaths. Nevertheless, the optimal amount of inspiratory effort to improve resp...

This report explores the efficacy of existing therapies for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), primarily in terms of clinically important outcomes such as the duration of mechanical ventilation and hospital mortality. Of the 15 therapies reviewed, the strongest evidence suggests that ALI/ARDS should be managed with a low-tidal-volume, pressure-limited approa...

Acute lung injury (ALI) is an inflammatory lung disease that manifests itself in patients as acute respiratory distress syndrome and thereby contributes significantly to the morbidity and mortality of patients experiencing critical illness. Even though it may seem counterintuitive, as the lungs are typically well-oxygenated organs, hypoxia signaling pathways have recently been implicated in the...

Cysteine-rich protein-61 (CYR61), also known as connective tissue growth factor, CYR61, and nephroblastoma overexpressed gene 1 (CCN1), is a heparin-binding protein member of the CCN family of matricellular proteins. Gene expression profiles showed that Cyr61 is upregulated in human acute lung injury (ALI), but its functional role is unclear. We hypothesized that CYR61 contributes to ALI in mic...

Submitted for the MAR05 Meeting of The American Physical Society Superfluidity of interacting bosons in one-dimension via strong disorder NOAH BRAY-ALI, UC Berkeley, Physics Department, JOEL MOORE, UC Berkeley, Physics Department; Lawrence Berkeley National Laboratory, Materials Science Division — We have found a novel set of superfluid and Mott insulating phases arising in strongly-disordered,...

This study aims to analyze online word-of-mouth regarding notebook computers, based on two large notebook computer forums in Taiwan. Online reviews are extracted between January 1, 2008 and April 1, 2010, with a total of 318 effective samples collected. Empirical study found that the market of the notebook computer can be divided into four groups, namely, game and entertainment, fashion and qua...

leishmaniasis is one of the most important parasitic diseases in terms of human injury and economic consequences which has a wide range of clinical protests of skin damage to fatal visceral discomfort covers. kala-azar is a mediterranean-type in and its main reservoirs are dogs and canine family. currently the most common disease centers are in parts of provinces such as ardebil, fars, east of ...

KEMAL ALI GER 1, PATRICIA ARNESON 1, CHARLES REMINGTON GOLDMAN 1 AND SWEE JOO TEH 2* 1 DEPARTMENT OF ENVIRONMENTAL SCIENCE AND POLICY, UNIVERSITY OF CALIFORNIA, DAVIS, CA 95616, USA AND AQUATIC TOXICOLOGY PROGRAM, DEPARTMENT OF ANATOMY, PHYSIOLOGY, AND CELL BIOLOGY, SCHOOL OF VETERINARY MEDICINE, DEPARTMENT OF ANATOMY, PHYSIOLOGY AND CELL BIOLOGY, UNIVERSITY OF CALIFORNIA, 1321 HARING HALL, ONE...

OBJECTIVES We observed early acute lung injury (ALI) after a switch from veno-arterial extracorporeal life support (VA-ECLS) to long-term mechanical circulatory support (MCS). The aim of our study was to analyse the frequency, impact on mortality and characteristics of patients presenting ALI after MCS implantation in the bridge-to-bridge (BTB) strategy. METHODS We retrospectively analysed da...

RATIONALE Acute lung injury (ALI) that develops 6 hours after transfusion (TRALI) is the leading cause of transfusion-related mortality. Several transfusion characteristics have been postulated as risk factors for TRALI, but the evidence is limited to retrospective studies. OBJECTIVES To compare patient and transfusion risk factors between patients who do and do not develop ALI. METHODS In ...