sigma(B), the general stress response sigma factor of Bacillus subtilis, is activated when the cell's energy levels decline or the bacterium is exposed to environmental stress (e.g., heat shock, ethanol). Physical stress activates sigma(B) through a collection of regulatory kinases and phosphatases (the Rsb proteins) which catalyze the release of sigma(B) from an anti-sigma(B) factor inhibitor....

A hallmark of sporulation of Bacillus subtilis is the formation of two distinct cells by an asymmetric division. The development programs in these two cells involve the compartmentalized activities of sigma E in the larger mother cell and of sigma F in the smaller prespore. Activation of sigma E requires expression of the sigma F-directed gene spoIIR. By immunofluorescence microscopy of a strai...

The results of GRANAT/SIGMA hard X-ray observations of GRS 1758–258 in 1990–1998 are presented. The source lies at ∼ 5 from the Galactic Center and was within the SIGMA field of view during the GRANAT surveys of this region. The total exposure time of the Galactic Center was 11×10 s. The regular SIGMA observations revealed strong variability of the source: the 40–150 keV flux varied at least by...

Sigma factors are multi-domain subunits of bacterial RNA polymerase (RNAP) that play critical roles in transcription initiation, including the recognition and opening of promoters as well as the initial steps in RNA synthesis. This review focuses on the structure and function of the major sigma-70 class that includes the housekeeping sigma factor (Group 1) that directs the bulk of transcription...

This research aims at presenting a fuzzy model to evaluate and select Six-Sigma projects.  For this purpose, a model of fuzzy analytic network process (ANP) was designed to consider the relation and mutual impact among the factors. In order to evaluate the projects, nine sub-criteria were considered which were classified into three categories of business, finance and procedural ones. Also to co...

This paper first enlists the generic problems of alloy wheel machining and subsequently details on the process improvement of the identified critical-to-quality machining characteristic of A356 aluminum alloy wheel machining process. The causal factors are traced using the Ishikawa diagram and prioritization of corrective actions is done through process failure modes and effects analysis. Proce...