Background: Lacerations are a common presenting complaint in the acute care setting. Current guidelines recommend the use of sterile technique for the exploration and closure of these wounds in order to reduce the risk of subsequent infection. Research in other medical specialties has cast doubt on the effectiveness of sterile gloves in lowering infection rates for uncomplicated procedures. The...

A two-dimensional continuum model of collective cell migration is used to predict the closure of gaps in intestinal epithelial cell layers. The model assumes that cell migration is governed by lamellipodia formation, cell-cell adhesion, and cell-substrate adhesion. Model predictions of the gap edge position and complete gap closure time are compared with experimental measures from cell layer sc...

OBJECTIVE The road to a headland that had become a suicide jumping hotspot was temporarily closed because of construction work. This created an opportunity to assess whether loss of vehicular access would lead to a reduction in suicides and emergency police callouts for threatened suicide at the site. METHOD Deaths at the headland were ascertained for a 10 year period before road closure and ...

A precise control over the meso- and microstructure of ordered and aligned nanoparticle assemblies, i.e., mesocrystals, is essential in the quest for exploiting the collective material properties for potential applications. In this work, we produced evaporation-induced self-assembled mesocrystals with different mesostructures and crystal habits based on iron oxide nanocubes by varying the nanoc...

Micrographia is a common, often presenting feature of Parkinson's disease. We assessed a simple writing paradigm in 40 PD patients "off" medications, 40 different PD patients "on" medications, and 64 age- and sex-matched controls. Patients wrote "Today is a nice day" with both eyes open and eyes closed to assess the effects of visual withdrawal (eyes closure). The order (eyes open vs. eyes clos...

It is natural to advance closures as atomic processes of universal evolution, and to analyze this concept specifically. Real complex systems like organisms and complex mechanisms cannot exist at either extreme of complete closure or lack of closure, nevertheless we should consider the properties of closures in general, the introduction of boundaries, a corresponding stability, the establishment...

We aimed to compare the recurrence rate following primary pterygium surgery using two different techniques, i.e. simple conjunctival closure (SCC) and rotational conjunctival flap (RCF). Postoperative discomfort and complications were also investigated in these patients.

Background: Sacrococcygeal pilonidal sinus is a common condition usually affecting young-to-middle-aged men. For managing sacrococcygeal illness, variety of lateralizing surgical flap procedures based on this principle have been published, including the Karydakis flap, Limberg modified Z-plasty, and Y-V advancement flap. Aim: To compare outcome simple excision with primary closure versus rhombo...

Simple theoretical concepts and models have been helpful to understand the folding rates and routes of single-domain proteins. As reviewed in this article, a physical principle that appears to underly these models is loop closure.

introduction: cleft lip (cl) and cleft palate (cp) are among the most common congenital anomalies. constituting 65% of head and neck anomalies in isolated or syndromic forms, they are considered as the most common head and neck congenital deformities in children. methods: 15 children from the tabriz children hospital were evaluated in this descriptive-analytic cross sectional study that possess...