Mechanisms leading to the obstruction of the microcirculation in sinusoidal obstruction syndrome (SOS) have been unclear. Because this occurs at the onset of disease, this is a potential key target for therapeutic intervention. Rats were treated with monocrotaline with or without continuous intraportal infusion of glutathione and were studied at 0.5, 1, 2, 4, 6, and 10 days after monocrotaline ...

An SN (sinusoids plus noise) model is a spectral model, in which the periodic components of the sound are represented by sinusoids with time-varying frequencies, amplitudes and phases. The remaining non-periodic components are represented by a filtered noise. The sinusoidal model utilizes physical properties of musical instruments and the noise model utilizes the human inability to perceive the...

The fixed dimension modified sinusoidal model (FDMSM) was recently proposed as an attractive candidate for compact representation of audio signals in adverse conditions. This paper aims to study the capability of the FDMSM signal representation for analysis and synthesis of speech mixtures as well as noisy audio signals corrupted by highly colored noise of babble and harmonic. Extensive simulat...

Auditory brainstem responses were measured in five normal-hearing subjects, using single-cycle sinusoids at octave frequencies ranging from 250 to 2000 Hz. These sinusoids, gated with Blackman functions, were presented either at 0 or 180 degree phase and were varied in level from 90 dB SPL to threshold in 10-dB steps. Stimulus phase affected wave V latencies for low-frequency stimuli, with the ...

In many practical applications, it turned out to be efficient to assume that the signal or an image is sparse, i.e., that when we decompose it into appropriate basic functions (e.g., sinusoids or wavelets), most of the coefficients in this decomposition will be zeros. At present, the empirical efficiency of sparsity-based techniques remains somewhat a mystery. In this paper, we show that fuzzy-...

In this work, an experimental technique is applied for the measurements of the vibrations and deformation of a test transformer core. Since the grid voltage contains some higher harmonics, in addition to a purely sinusoidal magnetisation of the core the presence of third harmonic is also studied. The vibrations of the transformer core for points as well as the surface scan of the leg show more ...

This paper presents the timbre model, a signal model which has been built to better understand the relationship between the perception of timbre and the musical sounds most commonly associated with timbre. In addition, an extension to the timbre model incorporating expressions is introduced. The presented work therefore has relation to a large field of science, including auditory perception, si...

Although sinusoidal models have been shown to be useful for timescale and pitch modiication of voiced speech, objectionable artifacts often arise when such models are applied to unvoiced speech. This correspondence presents a sinusoidal model-based speech modiication algorithm that preserves the natural character of unvoiced speech sounds after pitch and timescale modiication, eliminating commo...

the basic model for valuation of firm is the dividend discount model (ddm). when investors buy stocks, they expect to receive two types of cash flow: dividend in the period during which the stock is owned, and the expected sales price at the end of the period. in the extreme example, the investor keeps the stock until the company is liquidated; in such a case, the liquidating dividend becomes t...

Aquaporin 9 (AQP9) is a water channel membrane protein also permeable to small solutes such as urea, glycerol, and 5-fluorouracil, a chemotherapeutic agent. The objective of this study was to determine the cellular and subcellular localization of AQP9 in different organs of wild and AQP9 knockout mice (males and females) by immunohistochemistry ( IHC), immunofluorescence (IF) and RT-PCR. In add...