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تعداد نتایج: 1957741 فیلتر نتایج به سال:
Triplex DNA binders can effectively control copper-catalysed alkyne-azide click reactions in DNA architecture, such that either duplex or triplex DNA directed reactions of terminally attached azides and alkynes occur, in the absence or presence of triplex DNA binder, respectively.
M. Joerger1, A.D.R. Huitema2, H. Boot3, A. Cats3, V. Doodeman4, P. Smits4, L. Vainchtein2, H. Rosing2, I. Meijerman5, M. Zueger6, T.T. Cerny1, J.H.M. Beijnen2, J. Schellens7 Dept. of Oncology, Kantonsspital St. Gallen, St. Gallen, SWITZERLAND Department of Pharmacy&pharmacology, Slotervaart Hospital/The Netherlands Cancer Institute, Amsterdam, NETHERLANDS Department of Gastroenterology, Antoni ...
Background: Tumor radioresistance leads to a reduction in the efficiency of radiation therapy. It is very important to explore the cellular mechanisms leading to radioresistance and to find potential therapeutic targets, which might improve the efficacy of radiation therapy. This study was to investigate the role of ataxia-telangiectasia mutated (ATM) and murine double minute X (MDMX) in radior...
Supporting Results Structural Elucidation of [M+H] + m/z = 101.0232 Analysis of the n-butylamine-treated RNA from both E. coli and S. venezuelae indeed revealed the presence of a species consistent with the double addition of n-butylamine to the C4H4O3 unknown and the loss of two molecules of water (observed [M+H] + m/z = 211.1826; expected m/z for C12H23N2O= 211.1805. Treatment with d9-butylam...
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