The ability to specifically attach chemical probes to individual proteins represents a powerful approach to the study and manipulation of protein function in living cells. It provides a simple, robust and versatile approach to the imaging of fusion proteins in a wide range of experimental settings. However, a potential drawback of detection using chemical probes is the fluorescence background f...

Although the basic molecular components that promote regulated neurotransmitter release are well established, the contribution of these proteins as regulators of the plasticity of neurotransmission and refinement of synaptic connectivity during development is elaborated less fully. For example, during the period of synaptic growth and maturation in brain, the expression of synaptosomal protein ...

Although the United States has one of the highest standards of living in the world, nearly 15 percent of all households and 39 percent of near-poor households were food insecure in 2008. The Supplemental Nutrition Assistance Program (SNAP, formerly called the Food Stamp Program) is the cornerstone of federal food assistance programs and serves as the first line of defense against food-related h...

BACKGROUND Participation in the Supplemental Nutrition Assistance Program (SNAP) has been linked to an increased risk of obesity, but not much is known about the mechanisms behind this association. The objective of this study was to determine if the neighborhood density of unhealthy food outlets modifies the association between obesity and participation in SNAP. METHODS Data comes from the fi...

In the recent years, mobile computing platforms are becoming increasingly cheaper and yet more powerful in terms of computational resources. Automobiles provide a suitable environment to deploy such mobile platforms in order to provide low cost driver assistance systems. In this paper, we propose Snap-DAS which is a vision-based driver assistance system that is implemented on a SnapdragonTM emb...

Background: Essential tremor is characterized by several hyperkinetic movements, including arm and head tremors. We report another movement of the head in patients with essential tremor, which we term the ‘‘head snap.’’ This was observed as a jerking motion of the head in some patients while they performed the finger– nose–finger maneuver. Methods: We compared the prevalence of the head snap in...

Feline panleukopenia virus (FPV) is a significant pathogen of cats. Rapid virus detection is critical for treatment and management, especially in populations in which spread may occur. This study investigated the ability of the SNAP Canine Parvovirus Antigen Test Kit (SNAP Parvo, IDEXX Laboratories) to detect FPV with confirmation of viral identity by polymerase chain reaction (PCR) assay and g...

A snap-stabilizing protocol, starting from any arbitrary initial configuration, always behaves according to its specification. In this paper, we propose a light semi-automatic method allowing to snap-stabilize selfstabilizing wave protocols for arbitrary networks with a unique initiator. To that goal, we consider such a self-stabilizing protocol . We then slightly update to obtain a protocol th...

Several studies have associated reduced expression of synaptosomal-associated protein of 25 kDa (SNAP-25) with schizophrenia, yet little is known about its role in the illness. In this paper, a forebrain glutamatergic neuron-specific SNAP-25 knockout mouse model was constructed and studied to explore the possible pathogenetic role of SNAP-25 in schizophrenia. We showed that SNAP-25 conditional ...