Two aspirin tablets in 100 ml fluid will produce microscopical damage to the human stomach. A study was performed to determine whether a small amount of sodium bicarbonate (equivalent to one-third of a teaspoonful of baking soda) could protect against this damage. Sequential gastric biopsy specimens were taken from 15 healthy subjects before, during, and after intragastric instillation of one o...

BACKGROUND Lactic acidosis is a common cause of high anion gap metabolic acidosis. Sodium bicarbonate may be considered for an arterial pH <7.15 but paradoxically depresses cardiac performance and exacerbates acidosis by enhancing lactate production. This study aimed to evaluate the cause and mortality rate of lactic acidosis and to investigate the effect of factors, including sodium bicarbonat...

The effects of calcium propionate, sodium bicarbonate, and sodium ethylenediamine-tetraacetic acid (EDTA) on postharvest pathogens of apple and peach, and on improving the efficacy of the biocontrol product Aspire were evaluated. All three materials had a distinct inhibitory effect on the radial growth of Botrytis cinerea and Penicillium expansum in vitro. The inhibitory effect increased with t...

Dietary fructose, NaCl, and/or saturated fat have been correlated with mean arterial pressure (MAP) rises in sensitive strains of rats. Dysregulation of sodium and/or water reabsorption by the kidney may contribute. Using radiotelemetry and parallel semiquantitative immunoblotting, we examined the effects of various diets on MAP and the regulation of abundance of the major renal sodium and wate...

Metabolic acidosis has recently been observed in rat models of salt-sensitive genetic hypertension. To test the hypothesis that salt sensitivity in humans may be associated with abnormal acid-base homeostasis, we performed arterial blood gas analyses in young (20-31 years old) normotensive subjects (n = 40) who were placed on a low salt diet (20 mmol NaCl/day) for 2 weeks with either 200 mmol s...

debaryomyces hansenizopf isolated from the fructoplane of apples were found to be effective as biocontrol agent against rot of papaya caused by ulocladium. chartarum(pr.) simm. the ability of d. hansenii to prevent infection of u. chartarum was lost when the antagonist cells were killed by autoclaving. cell free culture filtrates of antagonist were unable to prevent disease incidence. efficacy ...

The electrogenic sodium bicarbonate cotransporter (NBCe1) is expressed in many epithelial cells and, in the brain, in glial cells. Little is known about the physiological significance of the NBCe1 for proton homeostasis and for other acid/base-coupled transporters in these cells. We have measured the voltage-dependent transport activity of an NBC from human kidney, type hkNBCe1, expressed in oo...